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Biology and significance of alpha‐fetoprotein in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer‐related
deaths globally due, in part, to the majority of patients being diagnosed with intermediate or …
deaths globally due, in part, to the majority of patients being diagnosed with intermediate or …
[HTML][HTML] Biomarkers in hepatocellular carcinoma: diagnosis, prognosis and treatment response assessment
Hepatocellular carcinoma (HCC) is one of the main cancer-related causes of death
worldwide. Thus, there is a constant search for improvement in screening, diagnosis, and …
worldwide. Thus, there is a constant search for improvement in screening, diagnosis, and …
[PDF][PDF] Alpha-fetoprotein as a potential surrogate biomarker for atezolizumab+ bevacizumab treatment of hepatocellular carcinoma
Purpose: Atezolizumab+ bevacizumab is the new standard of care for systemic treatment-
naive, unresectable hepatocellular carcinoma (HCC). This exploratory study investigated on …
naive, unresectable hepatocellular carcinoma (HCC). This exploratory study investigated on …
HCC and angiogenesis: possible targets and future directions
Hepatocellular carcinoma (HCC), the most common primary liver tumor, is notoriously
resistant to systemic therapies, and often recurs even after aggressive local therapies. HCCs …
resistant to systemic therapies, and often recurs even after aggressive local therapies. HCCs …
Ten years of sorafenib in hepatocellular carcinoma: Are there any predictive and/or prognostic markers?
G Marisi, A Cucchetti, P Ulivi, M Canale… - World journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Sorafenib has been considered the standard of care for patients with advanced
unresectable hepatocellular carcinoma (HCC) since 2007 and numerous studies have …
unresectable hepatocellular carcinoma (HCC) since 2007 and numerous studies have …
ACSL4 is a predictive biomarker of sorafenib sensitivity in hepatocellular carcinoma
J Feng, P Lu, G Zhu, SC Hooi, Y Wu, X Huang… - Acta Pharmacologica …, 2021 - nature.com
Sorafenib is the first-line treatment of advanced hepatocellular carcinoma (HCC). However,
there is a lack of validated biomarkers to predict sorafenib sensitivity. In this study we …
there is a lack of validated biomarkers to predict sorafenib sensitivity. In this study we …
[PDF][PDF] Progress and challenges of predictive biomarkers for immune checkpoint blockade
Y Lei, X Li, Q Huang, X Zheng, M Liu - Frontiers in Oncology, 2021 - frontiersin.org
Over the past decade, immune checkpoint blockade (ICB) therapy has revolutionized the
outlook for oncology with significant and sustained improvement in the overall patient …
outlook for oncology with significant and sustained improvement in the overall patient …
systemic treatment of hepatocellular carcinoma
M Pinter, M Peck‐Radosavljevic - Alimentary pharmacology & …, 2018 - Wiley Online Library
Background The approval of the tyrosine kinase inhibitor sorafenib in 2007 marked a
milestone in the treatment of hepatocellular carcinoma, as sorafenib was the first systemic …
milestone in the treatment of hepatocellular carcinoma, as sorafenib was the first systemic …
Presence of EpCAM‐positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma
K Schulze, C Gasch, K Staufer… - … journal of cancer, 2013 - Wiley Online Library
Current imaging technologies do not sufficiently detect micrometastasis and therefore do not
allow adequate stratification of patients with hepatocellular carcinoma (HCC) for curative or …
allow adequate stratification of patients with hepatocellular carcinoma (HCC) for curative or …
Comparison of tumor response by Response Evaluation Criteria in Solid Tumors (RECIST) and modified RECIST in patients treated with sorafenib for hepatocellular …
BACKGROUND: A significant improvement in overall survival (OS) was demonstrated in
patients with advanced hepatocellular carcinoma (HCC) who received sorafenib (Sor) in the …
patients with advanced hepatocellular carcinoma (HCC) who received sorafenib (Sor) in the …