Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023‏ - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies

EA Nunes, T Stokes, J McKendry… - … of Physiology-Cell …, 2022‏ - journals.physiology.org
Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …

[HTML][HTML] The age-related loss of skeletal muscle mass and function: Measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans

DJ Wilkinson, M Piasecki, PJ Atherton - Ageing research reviews, 2018‏ - Elsevier
Age-related loss of skeletal muscle mass and function, sarcopenia, is associated with
physical frailty and increased risk of morbidity (chronic diseases), in addition to all-cause …

Resistance training recommendations to maximize muscle hypertrophy in an athletic population: Position stand of the IUSCA

B Schoenfeld, J Fisher, J Grgic, C Haun… - … Journal of Strength …, 2021‏ - journal.iusca.org
Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of
a muscle fiber or whole muscle, and is due to increases in the size of pre-existing muscle …
JA Sanford, CD Nogiec, ME Lindholm, JN Adkins… - Cell, 2020‏ - cell.com
Exercise provides a robust physiological stimulus that evokes cross-talk among multiple
tissues that when repeated regularly (ie, training) improves physiological capacity, benefits …

Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations

MV Franchi, ND Reeves, MV Narici - Frontiers in physiology, 2017‏ - frontiersin.org
Skeletal muscle contracts either by shortening or lengthening (concentrically or
eccentrically, respectively); however, the two contractions substantially differ from one …