Cytotoxicity of metal‐based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations

P **ong, X Huang, N Ye, Q Lu, G Zhang… - Advanced …, 2022 - Wiley Online Library
Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐,
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …

Macrophage polarization in chronic inflammatory diseases: killers or builders?

L Parisi, E Gini, D Baci, M Tremolati… - Journal of …, 2018 - Wiley Online Library
Macrophages are key cellular components of the innate immunity, acting as the main player
in the first‐line defence against the pathogens and modulating homeostatic and …

Oridonin suppresses gastric cancer SGC‐7901 cell proliferation by targeting the TNF‐alpha/androgen receptor/TGF‐beta signalling pathway axis

S Gao, H Tan, D Li - Journal of Cellular and Molecular Medicine, 2023 - Wiley Online Library
Statistics provided by GLOBOCAN list gastric cancer as the sixth most common, with a
mortality ranking of third highest for the year 2020. In China, a herb called Rabdosia …

[HTML][HTML] The JNK signaling pathway in inflammatory skin disorders and cancer

MB Hammouda, AE Ford, Y Liu, JY Zhang - Cells, 2020 - mdpi.com
The c-Jun N-terminal kinases (JNKs), with its members JNK1, JNK2, and JNK3, is a
subfamily of (MAPK) mitogen-activated protein kinases. JNK signaling regulates a wide …

Immunotoxicity of metal and metal oxide nanoparticles: From toxic mechanisms to metabolism and outcomes

J Bi, C Mo, S Li, M Huang, Y Lin, P Yuan, Z Liu… - Biomaterials …, 2023 - pubs.rsc.org
The influence of metal and metal oxide nanomaterials on various fields since their discovery
has been remarkable. They have unique properties, and therefore, have been employed in …

MAP kinase pathways

DK Morrison - Cold Spring Harbor perspectives in …, 2012 - cshperspectives.cshlp.org
MAP Kinase Pathways Cold Spring Harbor Perspectives in Biology Skip to main page content
HOME ABOUT SUBJECT COLLECTIONS ARCHIVE SUBSCRIBE ADVERTISE ALERTS …

[HTML][HTML] The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation

A Plotnikov, E Zehorai, S Procaccia, R Seger - Biochimica et Biophysica …, 2011 - Elsevier
The MAPK cascades are central signaling pathways that regulate a wide variety of
stimulated cellular processes, including proliferation, differentiation, apoptosis and stress …

Kynurenines in CNS disease: regulation by inflammatory cytokines

BM Campbell, E Charych, AW Lee… - Frontiers in neuroscience, 2014 - frontiersin.org
The kynurenine pathway (KP) metabolizes the essential amino acid tryptophan and
generates a number of neuroactive metabolites collectively called the kynurenines …

[HTML][HTML] The role of PKC-MAPK signalling pathways in the development of hyperglycemia-induced cardiovascular complications

FF Jubaidi, S Zainalabidin, IS Taib… - International journal of …, 2022 - mdpi.com
Cardiovascular disease is the most common cause of death among diabetic patients
worldwide. Hence, cardiovascular wellbeing in diabetic patients requires utmost importance …

Anticancer mechanism of curcumin on human glioblastoma

SC Wong, MNA Kamarudin, R Naidu - Nutrients, 2021 - mdpi.com
Glioblastoma (GBM) is the most malignant brain tumor and accounts for most adult brain
tumors. Current available treatment options for GBM are multimodal, which include surgical …