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[HTML][HTML] Regulatory insights into nanomedicine and gene vaccine innovation: Safety assessment, challenges, and regulatory perspectives
This analysis explores the principal regulatory concerns linked to nanomedicines and gene
vaccines, including the complexities involved and the perspectives on how to navigate them …
vaccines, including the complexities involved and the perspectives on how to navigate them …
Dendritic cells in cancer immunology and immunotherapy
L Hato, A Vizcay, I Eguren, JL Pérez-Gracia… - Cancers, 2024 - mdpi.com
Simple Summary Although immune check point inhibitors have been established as a new
paradigm in cancer treatment, they have shown no clinical benefit in immune excluded or …
paradigm in cancer treatment, they have shown no clinical benefit in immune excluded or …
DNA vaccines: their formulations, engineering and delivery
M Kozak, J Hu - Vaccines, 2024 - mdpi.com
The concept of DNA vaccination was introduced in the early 1990s. Since then,
advancements in the augmentation of the immunogenicity of DNA vaccines have brought …
advancements in the augmentation of the immunogenicity of DNA vaccines have brought …
The future of cancer immunotherapy: DNA vaccines leading the way
A Pandya, Y Shah, N Kothari, H Postwala, A Shah… - Medical Oncology, 2023 - Springer
Immuno-oncology has revolutionized cancer treatment and has opened up new
opportunities for develo** vaccination methods. DNA-based cancer vaccines have …
opportunities for develo** vaccination methods. DNA-based cancer vaccines have …
Antigen cross-presentation by dendritic cells: A critical axis in cancer immunotherapy
C Moussion, L Delamarre - Seminars in Immunology, 2024 - Elsevier
Dendritic cells (DCs) are professional antigen-presenting cells that play a key role in
sha** adaptive immunity. DCs have a unique ability to sample their environment, capture …
sha** adaptive immunity. DCs have a unique ability to sample their environment, capture …
[HTML][HTML] Recent advances in cancer immunotherapy with a focus on FDA-approved vaccines and neoantigen-based vaccines
Cancer immunotherapies refer to the concept of retraining the immune system to target
malignant cells. Multiple immunotherapeutic options exist including immune modulating …
malignant cells. Multiple immunotherapeutic options exist including immune modulating …
A trinity nano-vaccine system with spatiotemporal immune effect for the adjuvant cancer therapy after radiofrequency ablation
M Li, A Jiang, H Han, M Chen, B Wang, Y Cheng… - ACS …, 2023 - ACS Publications
Cancer vaccine gains great attention with the advances in tumor immunology and
nanotechnology, but its long-term efficacy is restricted by the unsustainable immune activity …
nanotechnology, but its long-term efficacy is restricted by the unsustainable immune activity …
The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs
ED Namiot, D Smirnovová, AV Sokolov… - Frontiers in …, 2023 - frontiersin.org
Introduction: Clinical trials are the gold standard for testing new therapies. Databases like
ClinicalTrials. gov provide access to trial information, mainly covering the US and Europe. In …
ClinicalTrials. gov provide access to trial information, mainly covering the US and Europe. In …
[HTML][HTML] Advances in melanoma: from genetic insights to therapeutic innovations
F Valdez-Salazar, LA Jiménez-Del Rio… - Biomedicines, 2024 - mdpi.com
Advances in melanoma research have unveiled critical insights into its genetic and
molecular landscape, leading to significant therapeutic innovations. This review explores the …
molecular landscape, leading to significant therapeutic innovations. This review explores the …
Tumor-derived antigenic peptides as potential cancer vaccines
S Sotirov, I Dimitrov - International Journal of Molecular Sciences, 2024 - mdpi.com
Peptide antigens derived from tumors have been observed to elicit protective immune
responses, categorized as either tumor-associated antigens (TAAs) or tumor-specific …
responses, categorized as either tumor-associated antigens (TAAs) or tumor-specific …