Human mesenchymal stromal cell (MSC) lines can vary significantly in their functional
characteristics, and the effectiveness of MSC-based therapeutics may be realized by finding …

Understanding how defects in mechanotransduction affect cell‐to‐cell variability will add to
the fundamental knowledge of human pluripotent stem cell (hPSC) culture, and may suggest …

Pluripotent stem cells (PSCs) are important for future regenerative medicine therapies.
However, in the production of PSCs and derivatives, the control of culture-induced …

Automated cell segmentation and tracking is essential for dynamic studies of cellular
morphology, movement, and interactions as well as other cellular behaviors. However …

Genomic manipulation of human pluripotent stem cells (hPSCs) has become essential to
introduce genetic modifications and transgenes, and develop reporter lines. One of the …

Background Smooth muscle progenitor cells (pSMCs) differentiated from human pluripotent
stem cells (hPSCs) hold great promise for treating diseases or degenerative conditions …

We perform a detailed analysis of the migratory motion of human embryonic stem cells in
two-dimensions, both when isolated and in close proximity to another cell, recorded with …

Numerous biological approaches are available to characterise the mechanisms which
govern the formation of human embryonic stem cell (hESC) colonies. To understand how the …

Introducing or correcting disease-causing mutations through genome editing in human
pluripotent stem cells (hPSCs) followed by tissue-specific differentiation provide sustainable …

Introduction Understanding how extracellular matrix (ECM) protein composition regulates
the process of human induced pluripotent stem cell (hiPSC) colony formation may facilitate …