“The Tao begets the One. One begets all things of the world.” This quote from Tao Te Ching
is still inspiring for scientists in chemistry and materials science: The “One” can refer to a …

Forces play a pivotal role in life, and the response of live systems to forces requires
molecules and molecular interactions with adequate properties to counteract both in a …

Dynamic force spectroscopy probes the kinetic and thermodynamic properties of single
molecules and molecular assemblies. Here, we propose a simple procedure to extract …

The successful incorporation of enzymes into materials through multipoint covalent
immobilization (MPCI) has served as the foundation for numerous advances in diverse …

Although protein-folding studies began several decades ago, it is only recently that the tools
to analyze protein folding at the single-molecule level have been developed. Advances in …

Bundles of filamentous actin (F-actin) form primary structural components of a broad range
of cytoskeletal processes including filopodia, sensory hair cell bristles and microvilli. Actin …

Understanding how proteins fold into their native structure is a fundamental problem in
biophysics, crucial for protein design. It has been hypothesized that the formation of a molten …

One of the most exciting developments in the field of biological physics in recent years is the
ability to manipulate single molecules and probe their properties and function. Since its …

Single-molecule methods have given experimental access to the mechanical properties of
single protein molecules. So far, access has been limited to mostly one spatial direction of …

Recent advances in single molecule experiments have raised many challenges. These
challenges can be met by a proper understanding of the inter-and intra-molecular …