An overview on target-based drug design against kinetoplastid protozoan infections: Human African trypanosomiasis, Chagas disease and leishmaniases
The protozoan diseases Human African Trypanosomiasis (HAT), Chagas disease (CD), and
leishmaniases span worldwide and therefore their impact is a universal concern. The …
leishmaniases span worldwide and therefore their impact is a universal concern. The …
The drugs of slee** sickness: their mechanisms of action and resistance, and a brief history
H P. De Koning - Tropical Medicine and Infectious Disease, 2020 - mdpi.com
With the incidence of slee** sickness in decline and genuine progress being made
towards the WHO goal of eliminating slee** sickness as a major public health concern …
towards the WHO goal of eliminating slee** sickness as a major public health concern …
New global targets for NTDs in the WHO roadmap 2021–2030
A Casulli - PLoS neglected tropical diseases, 2021 - journals.plos.org
The second World Neglected Tropical Diseases (NTDs) Day was celebrated on 30 January
2021. To mark the occasion, the World Health Organization (WHO) launched its roadmap for …
2021. To mark the occasion, the World Health Organization (WHO) launched its roadmap for …
Review on Experimental Treatment Strategies Against Trypanosoma cruzi
AL Mazzeti, P Capelari-Oliveira, MT Bahia… - Journal of …, 2021 - Taylor & Francis
Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …
In vitro susceptibility of Trypanosoma cruzi discrete ty** units (DTUs) to benznidazole: A systematic review and meta-analysis
Background Chagas disease, a neglected tropical disease endemic to Latin America
caused by the parasite Trypanosoma cruzi, currently affects 6–7 million people and is …
caused by the parasite Trypanosoma cruzi, currently affects 6–7 million people and is …
Review of pharmacological options for the treatment of Chagas disease
F Lascano, F García Bournissen… - British journal of clinical …, 2022 - Wiley Online Library
Chagas disease (CD) is a worldwide problem, with over 8 million people infected in both
rural and urban areas. CD was first described over a century ago, but only two drugs are …
rural and urban areas. CD was first described over a century ago, but only two drugs are …
Dual and opposite roles of reactive oxygen species (ROS) in Chagas disease: beneficial on the pathogen and harmful on the host
Chagas disease is a neglected tropical disease, which affects an estimate of 6‐7 million
people worldwide. Chagas disease is caused by Trypanosoma cruzi, which is a eukaryotic …
people worldwide. Chagas disease is caused by Trypanosoma cruzi, which is a eukaryotic …
Incidence and Predictors of Progression to Chagas Cardiomyopathy: Long-Term Follow-Up of Trypanosoma cruzi–Seropositive Individuals
Background: There are few contemporary cohorts of Trypanosoma cruzi–seropositive
individuals, and the basic clinical epidemiology of Chagas disease is poorly understood …
individuals, and the basic clinical epidemiology of Chagas disease is poorly understood …
Of drugs and trypanosomatids: new tools and knowledge to reduce bottlenecks in drug discovery
Leishmaniasis (Leishmania species), slee** sickness (Trypanosoma brucei), and Chagas
disease (Trypanosoma cruzi) are devastating and globally spread diseases caused by …
disease (Trypanosoma cruzi) are devastating and globally spread diseases caused by …
Metallic nanoparticles and core-shell nanosystems in the treatment, diagnosis, and prevention of parasitic diseases
G Król, K Fortunka, M Majchrzak, E Piktel, P Paprocka… - Pathogens, 2023 - mdpi.com
The usage of nanotechnology in the fight against parasitic diseases is in the early stages of
development, but it brings hopes that this new field will provide a solution to target the early …
development, but it brings hopes that this new field will provide a solution to target the early …