Adipocyte differentiation is controlled by a tightly regulated transcriptional cascade in which
PPARγ and members of the C/EBP family are key players. Here we review the roles of …

Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated nuclear
receptor that regulates glucose and lipid metabolism, endothelial function and inflammation …

Regulatory T cells (Tregs) are a specific subset of lymphocytes that are critical for the
maintenance of self-tolerance. Expression levels of the transcription factor Foxp3 have been …

Adipocyte differentiation is tightly controlled by a transcriptional cascade, which directs the
extensive reprogramming of gene expression required to convert fibroblast-like precursor …

Microbe-derived acetate activates the Drosophila immunodeficiency (IMD) pathway in a
subset of enteroendocrine cells (EECs) of the anterior midgut. In these cells, the IMD …

Peroxisome proliferator-activated receptors (PPARs) belong to a family of ligand-activated
nuclear receptors that includes the estrogen, thyroid hormone, and glucocorticoid receptors …

Cell lineage specification is accomplished by a concerted action of chromatin remodeling
and tissue-specific transcription factors. However, the mechanisms that induce and maintain …

Differentiation of preadipocytes into mature adipocytes capable of efficiently storing lipids is
an important regulatory mechanism in obesity. Here, we examined the involvement of …

The article discusses posttranslational modifications of peroxisome proliferator-activated
receptors (PPAR)-y gene. PPAR are members of a nuclear receptor group of ligand …

The development of adipose tissue is a process which involves the concerted cooperation of
numerous transcription factors together with their coactivators and corepressors. The …