Hows and whys of tumor-seeking dyes

SM Usama, K Burgess - Accounts of chemical research, 2021‏ - ACS Publications
Conspectus Active targeting uses molecular fragments that bind receptors overexpressed on
cell surfaces to deliver cargoes, and this selective delivery to diseased over healthy tissue is …

NIR‐II cyanine@ albumin fluorophore for deep tissue imaging and imaging‐guided surgery

Y Zhang, Y Jia, S Zhu - SmartMat, 2024‏ - Wiley Online Library
Abstract The near‐infrared (NIR)‐II bioimaging technique is highly important for both
diagnosing and treating life‐threatening diseases due to its exceptional imaging …

Doubly Strapped Zwitterionic NIR‐I and NIR‐II Heptamethine Cyanine Dyes for Bioconjugation and Fluorescence Imaging

DH Li, RS Gamage, AG Oliver, NL Patel… - Angewandte …, 2023‏ - Wiley Online Library
Heptamethine cyanine dyes enable deep tissue fluorescence imaging in the near infrared
(NIR) window. Small molecule conjugates of the benchmark dye ZW800‐1 have been tested …

Role of albumin in accumulation and persistence of tumor-seeking cyanine dyes

SM Usama, GK Park, S Nomura, Y Baek… - Bioconjugate …, 2020‏ - ACS Publications
Some heptamethine cyanine dyes accumulate in solid tumors in vivo and persist there for
several days. The reasons why they accumulate and persist in tumors were incompletely …

A general approach to the design of high-performance near-infrared (NIR) D-π-A type fluorescent dyes

X Luo, J Li, J Zhao, L Gu, X Qian, Y Yang - Chinese Chemical Letters, 2019‏ - Elsevier
Near infrared (NIR) absorbing and emitting dyes are sought after for their potentials in
bioimaging and theranostic applications. They are typically not as stable as dyes absorbing …

Explorations into the Effect of meso‐Substituents in Tricarbocyanine Dyes: A Path to Diverse Biomolecular Probes and Materials

RM Exner, F Cortezon‐Tamarit… - Angewandte Chemie …, 2021‏ - Wiley Online Library
Polymethine cyanine dyes have been widely recognized as promising chemical tools for a
range of life science and biomedical applications, such as fluorescent staining of DNA and …

Research progress of near-infrared fluorescence probes based on indole heptamethine cyanine dyes in vivo and in vitro

C Sun, W Du, B Wang, B Dong, B Wang - BMC chemistry, 2020‏ - Springer
Near-infrared (NIR) fluorescence imaging is a noninvasive technique that provides
numerous advantages for the real-time in vivo monitoring of biological information in living …

Near‐Infrared Fluorophores Based on Heptamethine Cyanine Dyes: From Their Synthesis and Photophysical Properties to Recent Optical Sensing and Bioimaging …

NG Medeiros, CA Braga, VS Câmara… - Asian Journal of …, 2022‏ - Wiley Online Library
This review summarizes diverse synthetic methodologies to prepare a wide range of
heptamethine cyanine dyes, including symmetrical, unsymmetrical, and meso‐substituted …

High-affinity NIR-fluorescent inhibitors for tumor imaging via carbonic anhydrase IX

G Žvinys, A Petrosiute, A Zakšauskas… - Bioconjugate …, 2024‏ - pmc.ncbi.nlm.nih.gov
Tumor imaging and delivery of therapeutic agents may be achieved by designing high-
affinity and high-selectivity compounds recognizing a tumor cell-expressing biomarker, such …

A highly sensitive photoinitiating system based on pre-associated ion-pairs for NIR radical photopolymerization of optically clear materials

J Zhou, L Pitzer, C Ley, T Rölle, X Allonas - Polymer Chemistry, 2022‏ - pubs.rsc.org
A new highly reactive photoinitiating system based on a penta-methine cyanine dye and a
triarylalkylborate salt for radical photopolymerization reactions using near infra-red (NIR) …