Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR)
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …

A variety of nuclear magnetic resonance (NMR) applications have been developed for
structure-based drug discovery (SBDD). NMR provides many advantages over other …

Paramagnetic centers in biomolecules, such as specific metal ions that are bound to a
protein, affect the nuclei in their surrounding in various ways. One of these effects is the …

This article deals with the solution structure determination of paramagnetic metalloproteins
by NMR spectroscopy. These proteins were believed not to be suitable for NMR …

The paramagnetism of lanthanide ions offers outstanding opportunities for fast
determinations of the three-dimensional (3D) structures of protein− ligand complexes by …

Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags Page 1 1
Pseudocontact shifts in biomolecular NMR using paramagnetic metal tags Christoph …

NMR spectroscopy is a key method for studying the structure and dynamics of (large)
multidomain proteins and complexes in solution. It plays a unique role in integrated …

NMR spectroscopy is one of the most important methods for determining protein structures.
The scientific community is constantly pushing the limits of NMR spectroscopy by …

Molecules containing unpaired electrons affect the magnetic properties of nuclei in their
vicinity, which is observable in Nuclear Magnetic Resonance (NMR) spectra. As these …

The NMR determination of the structure of large biological macromolecules in solution is
primarily limited by the fast transverse relaxation that broadens lines and reduces spectral …