[HTML][HTML] The systemic nature of CKD
The accurate definition and staging of chronic kidney disease (CKD) is one of the major
achievements of modern nephrology. Intensive research is now being undertaken to unravel …
achievements of modern nephrology. Intensive research is now being undertaken to unravel …
Hypoxia-inducible factor activators in renal anemia: current clinical experience
NS Sanghani, VH Haase - Advances in chronic kidney disease, 2019 - Elsevier
Prolyl hydroxylase domain oxygen sensors are dioxygenases that regulate the activity of
hypoxia-inducible factor (HIF), which controls renal and hepatic erythropoietin production …
hypoxia-inducible factor (HIF), which controls renal and hepatic erythropoietin production …
[HTML][HTML] The renal pathology of obesity
N Tsuboi, Y Okabayashi, A Shimizu, T Yokoo - Kidney international reports, 2017 - Elsevier
Obesity causes various structural, hemodynamic, and metabolic alterations in the kidney.
Most of these are likely to be compensatory responses to the systemic increase in metabolic …
Most of these are likely to be compensatory responses to the systemic increase in metabolic …
HIF‐prolyl hydroxylases as therapeutic targets in erythropoiesis and iron metabolism
VH Haase - Hemodialysis international, 2017 - Wiley Online Library
A classic response to systemic hypoxia is the increase in red blood cell production. This
response is controlled by the prolyl hydroxylase domain/hypoxia‐inducible factor (HIF) …
response is controlled by the prolyl hydroxylase domain/hypoxia‐inducible factor (HIF) …
Pulmonary hypertension, mortality, and cardiovascular disease in CKD and ESRD patients: a systematic review and meta-analysis
M Tang, JA Batty, C Lin, X Fan, KE Chan… - American journal of kidney …, 2018 - Elsevier
Background Pulmonary hypertension is common in patients with chronic kidney disease
(CKD) and end-stage renal disease (ESRD) and may be associated with poor outcomes …
(CKD) and end-stage renal disease (ESRD) and may be associated with poor outcomes …
[HTML][HTML] Pulmonary hypertension in patients with chronic and end-stage kidney disease
ME Sise, AM Courtwright, RN Channick - Kidney international, 2013 - Elsevier
Pulmonary hypertension is defined as a mean pulmonary artery pressure≥ 25 mm Hg and
is a recently recognized complication of chronic kidney disease and end-stage renal …
is a recently recognized complication of chronic kidney disease and end-stage renal …
Prevalence, predictors, and outcomes of pulmonary hypertension in CKD
Pulmonary hypertension (PH) is associated with poor outcomes in the dialysis and general
populations, but its effect in CKD is unclear. We evaluated the prevalence and predictors of …
populations, but its effect in CKD is unclear. We evaluated the prevalence and predictors of …
[HTML][HTML] Pulmonary hypertension surveillance: United States, 2001 to 2010
MG George, LJ Schieb, C Ayala, A Talwalkar, S Levant - Chest, 2014 - Elsevier
Pulmonary hypertension (PH) is an uncommon but progressive condition, and much of what
we know about it comes from specialized disease registries. With expanding research into …
we know about it comes from specialized disease registries. With expanding research into …
[HTML][HTML] Cardiac complications of arteriovenous fistulas in patients with end-stage renal disease
Cardiovascular disease is the leading cause of the death in dialysis patients. Arteriovenous
fistulas (AVFs) are associated with lower mortality and are viewed as the desired access …
fistulas (AVFs) are associated with lower mortality and are viewed as the desired access …
Diagnosis and management of pulmonary hypertension in patients with CKD
Pulmonary hypertension (PH) is a highly prevalent and important condition in adults with
chronic kidney disease (CKD). In this review, we summarize the definition of PH, discuss its …
chronic kidney disease (CKD). In this review, we summarize the definition of PH, discuss its …