Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy

D Zhi, T Yang, J Yang, S Fu, S Zhang - Acta biomaterialia, 2020 - Elsevier
Among various nanoparticles, superparamagnetic iron oxide nanoparticles (SPIONs) have
been increasingly studied for their excellent superparamagnetism, magnetic heating …

Recent trends in antibody-based oncologic imaging

S Kaur, G Venktaraman, M Jain, S Senapati, PK Garg… - Cancer letters, 2012 - Elsevier
Antibodies, with their unmatched ability for selective binding to any target, are considered as
potentially the most specific probes for imaging. Their clinical utility, however, has been …

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging

C Grange, M Tapparo, S Bruno… - International …, 2014 - spandidos-publications.com
Mesenchymal stem cells (MSCs) contribute to the recovery of tissue injury, providing a
paracrine support. Cell-derived extracellular vesicles (EVs), carrying membrane and …

Mesoscale nanoparticles selectively target the renal proximal tubule epithelium

RM Williams, J Shah, BD Ng, DR Minton, LJ Gudas… - Nano …, 2015 - ACS Publications
We synthesized “mesoscale” nanoparticles, approximately 400 nm in diameter, which
unexpectedly localized selectively in renal proximal tubules and up to 7 times more …

Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting

JP Tiernan, SL Perry, ET Verghese, NP West… - British journal of …, 2013 - nature.com
Background: Colorectal cancer-specific biomarkers have been used as molecular targets for
fluorescent intra-operative imaging, targeted PET/MRI, and selective cytotoxic drug delivery …

Advances of engineered extracellular vesicles-based therapeutics strategy

H Komuro, S Aminova, K Lauro… - Science and Technology …, 2022 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous population of lipid bilayer membrane-
bound vesicles which encapsulate bioactive molecules, such as nucleic acids, proteins, and …

Near‐infrared molecular probes for in vivo imaging

X Zhang, S Bloch, W Akers… - Current protocols in …, 2012 - Wiley Online Library
Cellular and tissue imaging in the near‐infrared (NIR) wavelengths between 700 and 900
nm is advantageous for in vivo imaging because of the low absorption of biological …

[HTML][HTML] Image guided biodistribution and pharmacokinetic studies of theranostics

H Ding, F Wu - Theranostics, 2012 - ncbi.nlm.nih.gov
Image guided technique is playing an increasingly important role in the investigation of the
biodistribution and pharmacokinetics of drugs or drug delivery systems in various diseases …

Superparamagnetic iron oxide nanotheranostics for targeted cancer cell imaging and pH-dependent intracellular drug release

P Zou, Y Yu, YA Wang, Y Zhong, A Welton… - Molecular …, 2010 - ACS Publications
Studies were conducted to develop antibody-and fluorescence-labeled superparamagnetic
iron oxide nanoparticle (SPIO) nanotheranostics for magnetic resonance imaging (MRI) and …

Synthesizing and binding dual-mode poly (lactic-co-glycolic acid)(PLGA) nanobubbles for cancer targeting and imaging

JS Xu, J Huang, R Qin, GH Hinkle, SP Povoski… - Biomaterials, 2010 - Elsevier
Accurate assessment of tumor boundaries and recognition of occult disease are important
oncologic principles in cancer surgeries. However, existing imaging modalities are not …