Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

The endothelium that lines the interior of blood vessels is directly exposed to blood flow. The
shear stress arising from blood flow is “sensed” by the endothelium and is “transduced” into …

Shear stress regulates endothelial nitric oxide and superoxide (O2−·) production, implicating
the role of NADPH oxidase activity. It is unknown whether shear stress regulates the sources …

More recently, the correlation between exposure to nanoparticles and cardiovascular
diseases is of particular concern in nanotoxicology related fields. Nanoparticle-triggered …

The purpose of this work was to investigate the cardiovascular toxicity of different sizes and
different dosages of silica nanoparticles in Wistar rats. The three silica nanoparticles (30, 60 …

Leukocyte recruitment to endothelial cells is a critical event in inflammatory responses. The
spatial, temporal gradients of shear stress, topology, and outcome of cellular interactions …

BACKGROUND: Currently, no data are available on the direct comparison between the
Absorb everolimus-eluting bioresorbable vascular scaffold (Absorb BVS) and conventional …

Oxidized phospholipids, such as the products of the oxidation of 1-palmitoyl-2-arachidonoyl-
sn-glycero-3-phosphocholine by nonenzymatic radical attack, are known to be formed in a …