Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Smart molecular designs and applications of activatable organic photosensitizers
Photodynamic therapy (PDT)—which combines light, oxygen and photosensitizers (PS) to
generate reactive oxygen species—has emerged as an effective approach for targeted …
generate reactive oxygen species—has emerged as an effective approach for targeted …
Enzyme‐activatable near‐infrared hemicyanines as modular scaffolds for in vivo photodynamic therapy
Photodynamic therapy is an anti‐cancer treatment that requires illumination of
photosensitizers to induce local cell death. Current near‐infrared organic photosensitizers …
photosensitizers to induce local cell death. Current near‐infrared organic photosensitizers …
Tumor-microenvironment-activatable organic phototheranostic agents for cancer therapy
S Zeng, Z Guo, Y Hao, YS Kafuti, Z Yang, Q Yao… - Coordination Chemistry …, 2024 - Elsevier
Tumor microenvironment is a rather unusual circumstances formed during the growth of
tumor cells, showing significant differences from normal cells and tissues. Indeed, many …
tumor cells, showing significant differences from normal cells and tissues. Indeed, many …
Valkyrie Probes: A Novel Class of Enzyme‐Activatable Photosensitizers based on Sulfur‐and Seleno‐Rosamines with Pyridinium Unit
V Lioret, K Renault, O Maury… - Chemistry–An Asian …, 2023 - Wiley Online Library
The rational design of activatable photosensitizers (aPSs) uncaged by specific disease
biomarkers is currently booming due to their positive attributes to achieve targeted …
biomarkers is currently booming due to their positive attributes to achieve targeted …
A Supramolecularly Activatable Photosensitizer: Controllable Cyanine J-Aggregation for Efficient Photodynamic Therapy
H Ma, W Xu, X Tang, Y Kang, JF Xu… - CCS Chemistry, 2025 - chinesechemsoc.org
An activatable photosensitizer that could induce phototoxicity only in target sites is highly
demanded to overcome the potential off-target toxicity in photodynamic therapy. It is of great …
demanded to overcome the potential off-target toxicity in photodynamic therapy. It is of great …
Nitric Oxide Activatable Photodynamic Therapy Agents Based on BODIPY–Copper Complexes
In this work, two BODIPY–bipyridine Cu2+ ion complexes for targeted nitric oxide (NO)
activatable photodynamic therapy are reported. The design is based on the relatively high …
activatable photodynamic therapy are reported. The design is based on the relatively high …
Downregulation of gene expression in hypoxic cancer cells by an activatable G-quadruplex stabiliser
In the research, the modulation of gene expression with a novel G-quadruplex stabiliser was
analysed. Activation by the removal of bulky hypoxia-responsive substituent enhances G …
analysed. Activation by the removal of bulky hypoxia-responsive substituent enhances G …
Advancements in Dopamine Research: Exploring Resources, Therapeutic Potential, and Metabolism
N Kawatra, H Singh, S Negi, A Dubey… - Industrial Microbiology and …, 2024 - Springer
Dopamine is a predominant monoamine neurotransmitter that has a critical role in various
physiological processes like cardiovascular regulation, cognitive processes, and renal …
physiological processes like cardiovascular regulation, cognitive processes, and renal …
Reprograming cancer cells by a BODIPY G-quadruplex stabiliser
A Baser, B Basar, HB Dogan, G Sener… - Chemical …, 2023 - pubs.rsc.org
A cationic BODIPY-based G-quadruplex-selective stabiliser is developed and shown to
decrease cancer cell migration-invasion up to 90%. The expression of critical genes (HIF1α …
decrease cancer cell migration-invasion up to 90%. The expression of critical genes (HIF1α …