[HTML][HTML] The scientific case for brain simulations

GT Einevoll, A Destexhe, M Diesmann, S Grün, V Jirsa… - Neuron, 2019 - cell.com
A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …

Biological constraints on neural network models of cognitive function

F Pulvermüller, R Tomasello… - Nature Reviews …, 2021 - nature.com
Neural network models are potential tools for improving our understanding of complex brain
functions. To address this goal, these models need to be neurobiologically realistic …

[HTML][HTML] A dopamine gradient controls access to distributed working memory in the large-scale monkey cortex

S Froudist-Walsh, DP Bliss, X Ding, L Rapan, M Niu… - Neuron, 2021 - cell.com
Dopamine is required for working memory, but how it modulates the large-scale cortex is
unknown. Here, we report that dopamine receptor density per neuron, measured by …

Mechanisms of distributed working memory in a large-scale network of macaque neocortex

JF Mejias, XJ Wang - Elife, 2022 - elifesciences.org
Neural activity underlying working memory is not a local phenomenon but distributed across
multiple brain regions. To elucidate the circuit mechanism of such distributed activity, we …

[HTML][HTML] Neurobiological mechanisms for language, symbols and concepts: clues from brain-constrained deep neural networks

F Pulvermüller - Progress in Neurobiology, 2023 - Elsevier
Neural networks are successfully used to imitate and model cognitive processes. However,
to provide clues about the neurobiological mechanisms enabling human cognition, these …

Arbor—a morphologically-detailed neural network simulation library for contemporary high-performance computing architectures

N Abi Akar, B Cumming, V Karakasis… - 2019 27th euromicro …, 2019 - ieeexplore.ieee.org
We introduce Arbor, a performance portable library for simulation of large networks of multi-
compartment neurons on HPC systems. Arbor is open source software, developed under the …

Larger GPU-accelerated brain simulations with procedural connectivity

JC Knight, T Nowotny - Nature Computational Science, 2021 - nature.com
Simulations are an important tool for investigating brain function but large models are
needed to faithfully reproduce the statistics and dynamics of brain activity. Simulating large …

Connectivity concepts in neuronal network modeling

J Senk, B Kriener, M Djurfeldt, N Voges… - PLoS computational …, 2022 - journals.plos.org
Sustainable research on computational models of neuronal networks requires published
models to be understandable, reproducible, and extendable. Missing details or ambiguities …

[HTML][HTML] Open source brain: a collaborative resource for visualizing, analyzing, simulating, and develo** standardized models of neurons and circuits

P Gleeson, M Cantarelli, B Marin, A Quintana… - Neuron, 2019 - cell.com
Computational models are powerful tools for exploring the properties of complex biological
systems. In neuroscience, data-driven models of neural circuits that span multiple scales are …

Cell type-specific connectome predicts distributed working memory activity in the mouse brain

X Ding, S Froudist-Walsh, J Jaramillo, J Jiang… - elife, 2024 - elifesciences.org
Recent advances in connectomics and neurophysiology make it possible to probe whole-
brain mechanisms of cognition and behavior. We developed a large-scale model of the …