The difunctionalizative trifluoromethylation of unsaturated C− C bonds is a highly useful and
efficient method for the synthesis of trifluoromethyl compounds with attractive architectures …

Fluoro-containing heterocycles are widely applied in agricultural, medicinal, imaging,
materials science and other fields due to their unique physical and chemical properties …

The transformation of a large‐volume industrial by‐product and stable greenhouse gas
fluoroform (HCF3) to useful products has recently received significant attention. Now, a …

The azaindole chemical scaffold is represented in many biologically active natural products
and synthetic derivatives. Recently, this chemical scaffold yielded several therapeutic agents …

We herein describe a three-component reaction involving bicyclic amidines such as
DBN/DBU, acyl fluorides, and TMSCF3 for access to a novel class of N-acyl …

We herein present a flexible approach for the incorporation of CF3 units into a predefined
site of electron-rich alkenes that exploits the regiocontrolled introduction of an iodine handle …

Herein, the tandem synthesis of various CF3Se‐containing heterocyclic compounds has
been developed, using Tf2O as the catalyst and trifluoromethyl selenoxides as the …

An oxidative copper-mediated double trifluoromethylselenolation of terminal 2-
alkynylanilines using [(bpy) CuSeCF3] 2 is reported, providing a moderately efficient and …

We report here a radical hydrotrifluoromethylation of ynamides to provide an alternative
route toward β-CF3 enamides. By using PhICF3Cl as the CF3 reagent and DMF as the H …

In this paper, a copper (II)-catalyzed reaction of o-alkynylanilines with dimethylformamide
(DMF) in the presence of oxygen has been developed for synthesizing multisubstituted 3 …