Importance Prostate cancer is the second leading cause of cancer death among US men.
Objective To systematically review evidence on prostate-specific antigen (PSA)–based …

The definition of clinically significant prostate cancer is a dynamic process that was initiated
many decades ago, when there was already evidence that a great proportion of patients with …

The level of copy number alteration (CNA), termed CNA burden, in the tumor genome is
associated with recurrence of primary prostate cancer. Whether CNA burden is associated …

Prostate cancer (PCa) incidence and mortality have rapidly increased in China. Notably,
unique epidemiological characteristics of PCa are found in the Chinese PCa population …

Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …

Prostate cancer has a long disease history and a wide variety and uncertainty in individual
patients' clinical progress. In recent years, we have seen a revolutionary advance in both …

Purpose: To assess the applicability of active surveillance in patients with intermediate risk
prostate cancer, we compared the survival outcomes of patients with low risk and …

Prostate cancer (PCa) is the second most common cancer in men worldwide. A large
proportion of PCa are latent, never destined to progress or affect the patients' life. It is of …

Objectives Active surveillance (AS), now the standard of care for most men with favourable‐
risk prostate cancer, is appealing for selected men with 'favourable'intermediate‐risk …

The androgen receptor (AR) plays a predominant role in prostate cancer (PCa) pathology. It
consists of an N-terminal domain (NTD), a DNA-binding domain (DBD), a hinge region (HR) …