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Pathophysiology of chronic graft-versus-host disease and therapeutic targets
Chronic GVHD, an autoimmune disease that follows allogeneic hematopoietic-cell
transplantation, is characterized by infections and debilitating tissue injury leading to …
transplantation, is characterized by infections and debilitating tissue injury leading to …
[HTML][HTML] The biology of chronic graft-versus-host disease: a task force report from the National Institutes of Health Consensus Development Project on Criteria for …
Chronic graft-versus-host disease (GVHD) is the leading cause of late, nonrelapse mortality
and disability in allogeneic hematopoietic cell transplantation recipients and a major …
and disability in allogeneic hematopoietic cell transplantation recipients and a major …
Ruxolitinib for glucocorticoid-refractory chronic graft-versus-host disease
Background Chronic graft-versus-host disease (GVHD), a major complication of allogeneic
stem-cell transplantation, becomes glucocorticoid-refractory or glucocorticoid-dependent in …
stem-cell transplantation, becomes glucocorticoid-refractory or glucocorticoid-dependent in …
Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey
Despite major improvements in allogeneic hematopoietic cell transplantation over the past
decades, corticosteroid-refractory (SR) acute (a) and chronic (c) graft-versus-host disease …
decades, corticosteroid-refractory (SR) acute (a) and chronic (c) graft-versus-host disease …
Chronic graft-versus-host disease: biological insights from preclinical and clinical studies
KPA MacDonald, GR Hill… - Blood, The Journal of the …, 2017 - ashpublications.org
With the increasing use of mismatched, unrelated, and granulocyte colony-stimulating factor–
mobilized peripheral blood stem cell donor grafts and successful treatment of older …
mobilized peripheral blood stem cell donor grafts and successful treatment of older …
The intestinal microbiota in allogeneic hematopoietic cell transplant and graft-versus-host disease
Hematopoietic cell transplantation (HCT) is a critical treatment of patients with high-risk
hematopoietic malignancies, hematological deficiencies, and other immune diseases. In …
hematopoietic malignancies, hematological deficiencies, and other immune diseases. In …
Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
R Flynn, K Paz, J Du, DK Reichenbach… - Blood, The Journal …, 2016 - ashpublications.org
Chronic graft-versus-host disease (cGVHD) remains a major complication following
allogeneic bone marrow transplantation (BMT). The discovery of novel therapeutics is …
allogeneic bone marrow transplantation (BMT). The discovery of novel therapeutics is …
New and emerging therapies for acute and chronic graft versus host disease
LQ Hill, A Alousi, P Kebriaei, R Mehta… - Therapeutic …, 2018 - journals.sagepub.com
Graft versus host disease (GVHD) remains a major cause of morbidity and mortality
following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of …
following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of …
[HTML][HTML] Reprint of: acute graft-versus-host disease: novel biological insights
Graft-versus-host disease (GVHD) continues to be a leading cause of morbidity and mortality
after allogeneic hematopoietic stem cell transplantation. Recent insights into intestinal …
after allogeneic hematopoietic stem cell transplantation. Recent insights into intestinal …
Pathogenesis of acute graft‐versus‐host disease: from intestinal microbiota alterations to donor T cell activation
Acute graft‐versus‐host disease (aGVHD) is a major life‐threatening complication of
allogeneic haematopoietic cell transplantation (allo‐HCT). Here we discuss the aGVHD …
allogeneic haematopoietic cell transplantation (allo‐HCT). Here we discuss the aGVHD …