Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to
infection. Much has been focused on host response to pathogens mediated through the …

Sepsis is a major cause of morbidity and mortality worldwide. Sepsis-associated coagulation
disorders are involved in the pathogenesis of multiorgan failure and lead to a subsequently …

Purpose Capsaicin (8-methyl-N-geranyl-6-nonamide; CAP) is an alkaloid isolated from chili
peppers, which has complex pharmacological properties, including beneficial effects against …

The role of high-mobility group box-1 (HMGB1) in outcome prediction in sepsis is
controversial. Furthermore, its association with necroptosis, a programmed cell necrosis …

In folk medicine, Aloe, a genus of Aloaceae, is constantly developed into laxative drugs or
products and skin remedies with tremendous popularity worldwide. However, almost all …

Background MicroRNAs are dysregulated in sepsis. Acute lung injury is a progressive
syndrome during sepsis. However, the role of miR-129-5p in the development of acute lung …

High mobility group box protein 1 (HMGB1) is a biomolecule that acts as an alerting signal of
late sepsis by accelerating the production of proinflammatory cytokines, and eventually …

Many naturally derived compounds are currently used in oncotherapy. Besides official
medicine, complementary and alternative medicine practices, including old herbal remedies …

Aloin (ALO) is the major anthraquinone glycoside purified from the Aloe species. It is well
known for its anti-tumor effects. However, the protective effects of ALO in melanoma cancer …

Angelica gigas Nakai (AGN) root is a medicinal herbal widely used in traditional medicine in
Korea. AGN root ethanolic extract dietary supplements are marketed in the United States for …