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Endogenous retroviruses as modulators of innate immunity
E Russ, S Iordanskiy - Pathogens, 2023 - mdpi.com
Endogenous retroviruses (ERVs), or LTR retrotransposons, are a class of transposable
elements that are highly represented in mammalian genomes. Human ERVs (HERVs) make …
elements that are highly represented in mammalian genomes. Human ERVs (HERVs) make …
Nomenclature for endogenous retrovirus (ERV) loci
Retroviral integration into germline DNA can result in the formation of a vertically inherited
proviral sequence called an endogenous retrovirus (ERV). Over the course of their …
proviral sequence called an endogenous retrovirus (ERV). Over the course of their …
Transposable elements in mammals promote regulatory variation and diversification of genes with specialized functions
LN van de Lagemaat, JR Landry, DL Mager… - TRENDS in …, 2003 - cell.com
Nearly half of mammalian genomes are derived from ancient transposable elements (TEs).
We analyzed the prevalence of TEs in untranslated regions of human and mouse mRNAs …
We analyzed the prevalence of TEs in untranslated regions of human and mouse mRNAs …
[HTML][HTML] Epigenetic control of human endogenous retrovirus expression: focus on regulation of long-terminal repeats (LTRs)
Transposable elements, including endogenous retroviruses (ERVs), comprise almost 45%
of the human genome. This could represent a significant pathogenic burden but it is …
of the human genome. This could represent a significant pathogenic burden but it is …
Identification and characterization of novel human endogenous retrovirus families by phylogenetic screening of the human genome map** project database
M Tristem - Journal of virology, 2000 - journals.asm.org
Human endogenous retroviruses (HERVs) were first identified almost 20 years ago, and
since then numerous families have been described. It has, however, been difficult to obtain a …
since then numerous families have been described. It has, however, been difficult to obtain a …
RNAs from all categories generate retrosequences that may be exapted as novel genes or regulatory elements
J Brosius - Gene, 1999 - Elsevier
While the significance of middle repetitive elements had been neglected for a long time,
there are again tendencies to ascribe most members of a given middle repetitive sequence …
there are again tendencies to ascribe most members of a given middle repetitive sequence …
Human endogenous retrovirus K solo-LTR formation and insertional polymorphisms: implications for human and viral evolution
Human endogenous retroviruses (HERVs) are a potential source of genetic diversity in the
human genome. Although many of these elements have been inactivated over time by the …
human genome. Although many of these elements have been inactivated over time by the …
Retroviruses and primate evolution
ED Sverdlov - Bioessays, 2000 - Wiley Online Library
Human endogenous retroviruses (HERVs), probably representing footprints of ancient germ‐
cell retroviral infections, occupy about 1% of the human genome. HERVs can influence …
cell retroviral infections, occupy about 1% of the human genome. HERVs can influence …
Long terminal repeats are used as alternative promoters for the endothelin B receptor and apolipoprotein CI genes in humans
To examine the potential regulatory involvement of retroelements in the human genome, we
screened the transcribed sequences of GenBank TM and expressed sequence tag data …
screened the transcribed sequences of GenBank TM and expressed sequence tag data …
Genomic scrap yard: how genomes utilize all that junk
W Makałowski - Gene, 2000 - Elsevier
Interspersed repetitive sequences are major components of eukaryotic genomes. Repetitive
elements comprise over 50% of the mammalian genome. Because the specific function of …
elements comprise over 50% of the mammalian genome. Because the specific function of …