Pruritus (or itch) is an unpleasant sensation leading to a desire to scratch. In the epidermis,
there are selective C or Aδ epidermal nerve endings that are pruriceptors. At their other …

Until recently, itch pathophysiology was poorly understood and treatments were poorly
effective in relieving itch. Current progress in our knowledge of the itch processing, the …

Itch is an annoying sensation consisting of both sensory and emotional components. It is
known to involve the parabrachial nucleus (PBN), but the following transmission nodes …

Itch is a sensation defined as the urge to scratch. The central mechanisms of itch are being
increasingly studied. These studies are usually based on experimental itch induction …

Itch is an unpleasant sensation that evokes a desire to scratch. Itch processing in the
peripheral and spinal cord has been studied extensively, but the mechanism of itch in the …

The International Association for the Study of Pain (IASP) defined three descriptors for pain:
nociceptive pain is “pain that arises from actual or threatened damage to non neural tissue …

Pruritus of chronic spontaneous urticaria (CSU) is one of the most common and irritating
sensations that severely affects the quality of life. However, the changes in the functional …

Background and purpose Chronic itch is one of the most common irritating sensations, yet its
mechanisms have not been fully elucidated. Although some studies have revealed …

Background Patients with chronic pruritus (CP) have a low quality of life, thus it is important
to gain a better understanding of the underlying processes. Previous functional magnetic …

Background Burn injuries cause significant motor and sensory dysfunctions that can
negatively impact burn survivors' quality of life. The underlying mechanisms of these burn …