Drug resistance in cancer cells significantly diminishes treatment efficacy, leading to
recurrence and metastasis. A critical factor contributing to this resistance is the epigenetic …

Sepsis, a severe condition instigated by infections, continues to be a primary global cause of
death, typified by systemic inflammation and advancing immune dysfunction …

Sepsis is one of the major causes of death in the hospital worldwide. The pathology of
sepsis is tightly associated with dysregulation of innate immune responses. The contribution …

Abstract RNA N6-methladenosine (m6A) regulators are required for a variety of biological
processes, including immune responses, and increasing evidence indicates that their …

Neutrophils play a critical role in the immune response to infection and tissue injury.
However, recent studies have shown that neutrophils are a heterogeneous population with …

Abstract N6-methyladenosine (m6A), a posttranscriptional regulatory mechanism, is the
most common epigenetic modification in mammalian mRNA. M6A modifications play a …

As a grave and highly lethal clinical challenge, sepsis, along with its consequent multiorgan
dysfunction, affects millions of people worldwide. Sepsis is a complex syndrome caused by …

Sepsis is one of the life-threatening diseases worldwide. Despite the continuous progress in
medicine, the specific mechanism of sepsis remains unclear. A key strategy of pathogens is …

Disuse bone loss is prone to occur in individuals who lack mechanical stimulation due to
prolonged spaceflight or extended bed rest, rendering them susceptible to fractures and …

Background: Inflammatory responses, apoptosis, and oxidative stress, are key factors that
contribute to hepatic ischemia/reperfusion (I/R) injury, which may lead to the failure of liver …