Conventional cancer chemotherapy is often associated with toxicity issues. Thus, new drug
delivery systems (DDSs) are developed as alternatives owing to their potential to selectively …

Microbubbles (MBs) were observed for the first time in vivo as a curious consequence of
quick saline injection during ultrasound (US) imaging of the aortic root, more than 50 years …

Although antibodies are well developed and widely used in cancer therapy and diagnostic
fields, some defects remain, such as poor tissue penetration, long in vivo metabolic …

In the last decade, molecular ultrasound imaging has been rapidly progressing. It has
proven promising to diagnose angiogenesis, inflammation, and thrombosis, and many …

Tumors are often characterized by hypoxia, vascular abnormalities, low extracellular pH,
increased interstitial fluid pressure, altered choline-phospholipid metabolism, and aerobic …

Ovarian cancer is the deadliest gynecological disease among US women. Poor 5-year
survival rates (< 30%) are due to presentation of most women at diagnosis with advanced …

Contrast-enhanced ultrasound (CEUS) is a safe, relatively inexpensive, and widely
available imaging technique using dedicated imaging ultrasound sequences and FDA …

As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain
overcome antibody size and complexity while maintaining analogous binding loops …

Although considerable efforts have been conducted to diagnose, improve, and treat cancer
in the past few decades, existing therapeutic options are insufficient, as mortality and …

Diabetes vasculopathy is a significant complication of diabetes mellitus (DM), and early
identification and timely intervention can effectively slow the progression. Accumulating …