Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …

Kinesin-1 is a typical motile molecular motor and the founding member of the kinesin family.
The most significant feature in the unidirectional motion of kinesin-1 is its processivity. To …

The microtubule cytoskeleton forms complex macromolecular assemblies with a range of
microtubule-associated proteins (MAPs) that have fundamental roles in cell architecture …

The kinesin-3 motor KIF1A functions in neurons, where its fast and superprocessive motility
facilitates long-distance transport, but little is known about its force-generating properties …

RNA editing is a widespread epigenetic process that can alter the amino acid sequence of
proteins, termed" recoding." In cephalopods, most transcripts are recoded, and recoding is …

Kinesins drive the transport of cellular cargoes as they walk along microtubule tracks;
however, recent work has suggested that the physical act of kinesins walking along …

Microtubules (MTs) and their associated proteins play essential roles in maintaining cell
structure, organelle transport, cell motility, and cell division. Two motors, kinesin and …

The mechanochemical coupling of ATPase hydrolysis and conformational dynamics in
kinesin motors facilitates intramolecular interaction cycles between the kinesin motor and …

KIF20A is a critical kinesin for cell division and a promising anti-cancer drug target. The
mechanisms underlying its cellular roles remain elusive. Interestingly, unusual coupling …

Several kinesin-5 motors (kinesin-5s) exhibit bidirectional motility. The mechanism of such
motility remains unknown. Bidirectional kinesin-5s share a long N-terminal nonmotor …