The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Z Zhang, M Kang, H Tan, N Song, M Li, P ** Type‐I photosensitizers is considered as an efficient approach to overcome the
deficiency of traditional photodynamic therapy (PDT) for hypoxic tumors. However, it remains …

Acceptor Planarization and Donor Rotation: A Facile Strategy for Realizing Synergistic Cancer Phototherapy via Type I PDT and PTT

L Feng, C Li, L Liu, Z Wang, Z Chen, J Yu, W Ji… - ACS …, 2022 - ACS Publications
Tumor hypoxia seriously impairs the therapeutic outcomes of type II photodynamic therapy
(PDT), which is highly dependent upon tissue oxygen concentration. Herein, a facile strategy …

Recent advances of AIE light-up probes for photodynamic therapy

S Liu, G Feng, BZ Tang, B Liu - Chemical science, 2021 - pubs.rsc.org
As a new non-invasive treatment method, photodynamic therapy (PDT) has attracted great
attention in biomedical applications. The advantages of possessing fluorescence for …

Engineering of BODIPY-based theranostics for cancer therapy

Z Mao, JH Kim, J Lee, H **ong, F Zhang… - Coordination Chemistry …, 2023 - Elsevier
In recent years, BODIPY-based theranostics have increasingly been used in cancer therapy
and have achieved significant success. According to photochemical theories, the optical …

An unexpected strategy to alleviate hypoxia limitation of photodynamic therapy by biotinylation of photosensitizers

J An, S Tang, G Hong, W Chen, M Chen, J Song… - Nature …, 2022 - nature.com
The most common working mechanism of photodynamic therapy is based on high-toxicity
singlet oxygen, which is called Type II photodynamic therapy. But it is highly dependent on …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021 - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

A supramolecular photosensitizer derived from an Arene-Ru (II) complex self-assembly for NIR activated photodynamic and photothermal therapy

G Xu, C Li, C Chi, L Wu, Y Sun, J Zhao, XH **a… - Nature …, 2022 - nature.com
Effective photosensitizers are of particular importance for the widespread clinical utilization
of phototherapy. However, conventional photosensitizers are usually plagued by short …

A Highly Water‐Soluble Aggregation‐Induced Emission Luminogen with Anion‐π+ Interactions for Targeted NIR Imaging of Cancer Cells and Type I Photodynamic …

L Liu, C Li, J Gong, Y Zhang, W Ji, L Feng… - Angewandte …, 2023 - Wiley Online Library
The low oxygen dependence of type I photosensitizers (PSs) has made them a popular
choice for treating solid tumors. However, the drawbacks of poor water solubility, short …