The African turquoise killifish: A research organism to study vertebrate aging and diapause

CK Hu, A Brunet - Aging cell, 2018 - Wiley Online Library
The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

Sexual Dimorphisms in Innate Immunity and Responses to Infection in Drosophila melanogaster

RL Belmonte, MK Corbally, DF Duneau… - Frontiers in …, 2020 - frontiersin.org
The sexes show profound differences in responses to infection and the development of
autoimmunity. Dimorphisms in immune responses are ubiquitous across taxa, from …

The microbiome stabilizes circadian rhythms in the gut

Y Zhang, Y Li, AF Barber, SB Noya… - Proceedings of the …, 2023 - National Acad Sciences
The gut microbiome is well known to impact host physiology and health. Given widespread
control of physiology by circadian clocks, we asked how the microbiome interacts with …

[HTML][HTML] Microbiota-derived lactate activates production of reactive oxygen species by the intestinal NADPH oxidase Nox and shortens Drosophila lifespan

I Iatsenko, JP Boquete, B Lemaitre - Immunity, 2018 - cell.com
Commensal microbes colonize the gut epithelia of virtually all animals and provide several
benefits to their hosts. Changes in commensal populations can lead to dysbiosis, which is …

Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour

SF Henriques, DB Dhakan, L Serra… - Nature …, 2020 - nature.com
The impact of commensal bacteria on the host arises from complex microbial-diet-host
interactions. Map** metabolic interactions in gut microbial communities is therefore key to …

Gut microbiome modulates Drosophila aggression through octopamine signaling

Y Jia, S **, K Hu, L Geng, C Han, R Kang… - Nature …, 2021 - nature.com
Gut microbiome profoundly affects many aspects of host physiology and behaviors. Here we
report that gut microbiome modulates aggressive behaviors in Drosophila. We found that …

Drosophila melanogaster establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria

IS Pais, RS Valente, M Sporniak, L Teixeira - PLoS biology, 2018 - journals.plos.org
Animals live together with diverse bacteria that can impact their biology. In Drosophila
melanogaster, gut-associated bacterial communities are relatively simple in composition but …

The Intestine of Drosophila melanogaster: An Emerging Versatile Model System to Study Intestinal Epithelial Homeostasis and Host-Microbial Interactions in Humans

F Capo, A Wilson, F Di Cara - Microorganisms, 2019 - mdpi.com
In all metazoans, the intestinal tract is an essential organ to integrate nutritional signaling,
hormonal cues and immunometabolic networks. The dysregulation of intestinal epithelium …

Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA …

M Kapun, MG Barrón, F Staubach… - Molecular Biology …, 2020 - academic.oup.com
Genetic variation is the fuel of evolution, with standing genetic variation especially important
for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of …

Generation of axenic Aedes aegypti demonstrate live bacteria are not required for mosquito development

MA Correa, B Matusovsky, DE Brackney… - Nature …, 2018 - nature.com
The mosquito gut microbiome plays an important role in mosquito development and fitness,
providing a promising avenue for novel mosquito control strategies. Here we present a …