Antimicrobial photodynamic therapy: Latest developments with a focus on combinatory strategies

R Youf, M Müller, A Balasini, F Thétiot, M Müller… - Pharmaceutics, 2021 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …

Antimicrobial blue light: A 'Magic Bullet'for the 21st century and beyond?

LG Leanse, C Dos Anjos, S Mushtaq, T Dai - Advanced drug delivery …, 2022 - Elsevier
Over the past decade, antimicrobial blue light (aBL) at 400− 470 nm wavelength has
demonstrated immense promise as an alternative approach for the treatment of multidrug …

Combating drug-resistant helicobacter pylori infection with zinc peroxide-based nanoparticles: a ROS reservoir via photochemical reaction

KI Wong, S Wang, M Li, G Zhao, C Wang, L Wu… - Chemical Engineering …, 2024 - Elsevier
Addressing the challenge of treating Helicobacter pylori infection while ensuring the safety
of other microorganisms, such as intestinal microbiota, is of paramount importance. In this …

Antibacterial, antiviral, and antifungal activities of quinine and its derivatives: A narrative mini-review

MR Mohammadi, E Rezaei Niaraki - Micro Nano Bio Aspects, 2023 - mnba-journal.com
Quinine sulfate, the main active compound from quinine extract, has been applied as an old
drug under the category of a limited over-the-counter drug. This compound is a medication …

The microbicidal potential of visible blue light in clinical medicine and public health

D Haridas, CD Atreya - Frontiers in Medicine, 2022 - frontiersin.org
Visible blue light of wavelengths in the 400–470 nm range has been observed to have
microbicidal properties. A widely accepted hypothesis for the mechanism of microbial …

Chromophore-targeting precision antimicrobial phototherapy

S Jusuf, PT Dong - Cells, 2023 - mdpi.com
Phototherapy, encompassing the utilization of both natural and artificial light, has emerged
as a dependable and non-invasive strategy for addressing a diverse range of illnesses …

[HTML][HTML] Photoinactivation of catalase sensitizes a wide range of bacteria to ROS-producing agents and immune cells

PT Dong, S Jusuf, J Hui, Y Zhan, Y Zhu, GY Liu… - JCI insight, 2022 - ncbi.nlm.nih.gov
Bacteria have evolved to cope with the detrimental effects of ROS using their essential
molecular components. Catalase, a heme-containing tetramer protein expressed universally …

[HTML][HTML] Nanoparticle enhanced blue light therapy

R Akasov, EV Khaydukov, M Yamada… - Advanced drug delivery …, 2022 - Elsevier
As antimicrobial resistance continues to compromise the therapeutic efficacy of countless
antibiotics, the significant risk this poses to the global population is without question and …

Light-Mediated Decreases in Cyclic di-GMP Levels Inhibit Structure Formation in Pseudomonas aeruginosa Biofilms

LJ Kahl, A Price-Whelan, LEP Dietrich - Journal of bacteriology, 2020 - Am Soc Microbiol
Light is known to trigger regulatory responses in diverse organisms, including slime molds,
animals, plants, and phototrophic bacteria. However, light-dependent processes in …

Blue light potentiates antibiotics in bacteria via parallel pathways of hydroxyl radical production and enhanced antibiotic uptake

LG Leanse, C Anjos, KR Kaler, J Hui… - Advanced …, 2023 - Wiley Online Library
In the age of antimicrobial resistance, the urgency by which novel therapeutic approaches
need to be introduced into the clinical pipeline has reached critical levels. Antimicrobial blue …