Methods for the directed evolution of proteins

MS Packer, DR Liu - Nature Reviews Genetics, 2015 - nature.com
Directed evolution has proved to be an effective strategy for improving or altering the activity
of biomolecules for industrial, research and therapeutic applications. The evolution of …

Genomic innovation for crop improvement

MW Bevan, C Uauy, BBH Wulff, J Zhou, K Krasileva… - Nature, 2017 - nature.com
Crop production needs to increase to secure future food supplies, while reducing its impact
on ecosystems. Detailed characterization of plant genomes and genetic diversity is crucial …

Convergent selection of a WD40 protein that enhances grain yield in maize and rice

W Chen, L Chen, X Zhang, N Yang, J Guo, M Wang… - Science, 2022 - science.org
A better understanding of the extent of convergent selection among crops could greatly
improve breeding programs. We found that the quantitative trait locus KRN2 in maize and its …

Genome sequencing reveals evidence of adaptive variation in the genus Zea

L Chen, J Luo, M **, N Yang, X Liu, Y Peng, W Li… - Nature Genetics, 2022 - nature.com
Maize is a globally valuable commodity and one of the most extensively studied genetic
model organisms. However, we know surprisingly little about the extent and potential utility …

Wild emmer genome architecture and diversity elucidate wheat evolution and domestication

R Avni, M Nave, O Barad, K Baruch, SO Twardziok… - Science, 2017 - science.org
Wheat (Triticum spp.) is one of the founder crops that likely drove the Neolithic transition to
sedentary agrarian societies in the Fertile Crescent more than 10,000 years ago. Identifying …

Genome-wide selection and genetic improvement during modern maize breeding

B Wang, Z Lin, X Li, Y Zhao, B Zhao, G Wu, X Ma… - Nature Genetics, 2020 - nature.com
Since the development of single-hybrid maize breeding programs in the first half of the
twentieth century, maize yields have increased over sevenfold, and much of that increase …

Evolution of crop species: genetics of domestication and diversification

RS Meyer, MD Purugganan - Nature reviews genetics, 2013 - nature.com
Domestication is a good model for the study of evolutionary processes because of the recent
evolution of crop species (< 12,000 years ago), the key role of selection in their origins, and …

Back into the wild—Apply untapped genetic diversity of wild relatives for crop improvement

H Zhang, N Mittal, LJ Leamy, O Barazani… - Evolutionary …, 2017 - Wiley Online Library
Deleterious effects of climate change and human activities, as well as diverse environmental
stresses, present critical challenges to food production and the maintenance of natural …

Seed filling in domesticated maize and rice depends on SWEET-mediated hexose transport

D Sosso, D Luo, QB Li, J Sasse, J Yang, G Gendrot… - Nature …, 2015 - nature.com
Carbohydrate import into seeds directly determines seed size and must have been
increased through domestication. However, evidence of the domestication of sugar …

Tracing the ancestry of modern bread wheats

C Pont, T Leroy, M Seidel, A Tondelli, W Duchemin… - Nature …, 2019 - nature.com
Abstract For more than 10,000 years, the selection of plant and animal traits that are better
tailored for human use has shaped the development of civilizations. During this period …