Vaccination serves as a cornerstone of global health. Successful prevention of infection or
disease by vaccines is achieved through elicitation of pathogen-specific antibodies and long …

Latest research shows that SERPINE1 overexpression has an important role in Coronavirus
2019 (COVID-19)-associated coagulopathy leading to acute respiratory distress syndrome …

Background Activated cardiac fibroblasts (CF) play a central role in cardiac fibrosis, a
condition associated with most cardiovascular diseases. Conversion of quiescent into …

Background Evidence revealed that age could affect immune responses in patients with the
acute respiratory syndrome of coronavirus 2 (SARS-CoV-2) infection. This study investigated …

Prion diseases are a group of neurodegenerative disorders characterized by the
accumulation of misfolded prion protein (called PrPSc). Although conversion of the cellular …

Background Serine protease inhibitors clade B serpins (SERPINBs) are the largest subclass
of protease inhibitors, once thought of as a tumor suppressor gene family. However, some …

The acute respiratory syndrome coronavirus (SARS-CoV-2) has spread across the world,
resulting in a pandemic COVID-19 which is a human zoonotic disease that is caused by a …

In bee venoms, low–molecular-weight peptides, including serine protease inhibitors (SPIs),
exhibit multifunctional activities. Although SPIs in bee venoms are relatively well known …

Purpose: The persistent pandemic of coronavirus disease 2019 (COVID-19), the discovery
of gastrointestinal transmission routes and the possible susceptibility of cancer patients to …

Serine protease inhibitors (Serpins) are a protein superfamily of protease inhibitors that are
thought to play a role in the regulation of inflammation, immunity, tumorigenesis …