Perspectives Page 1 Perspectives Neutrophil-activating Peptide-1/lnterleukin 8, a Novel
Cytokine That Activates Neutrophils Marco Baggiolini,* Alfred Walz,* and Steven L. Kunkel …

Publisher Summary This chapter focuses on interleukin-8 (IL-8) and related chemotactic
cytokines—namely, CXC and CC chemokines. IL-8 is the best known member of a new …

In this study, we demonstrate that the CXC family of chemokines displays disparate
angiogenic activity depending upon the presence or absence of the ELR motif. CXC …

Movement of neutrophils from the bloodstream to inflamed tissue depends on the activation
of both the neutrophil and the endothelial cell. Endothelial cells lining the postcapillary …

A number of novel chemotactic cytokines are becoming increasingly recognized as
important participants in the elicitation of specific inflammatory cells from the peripheral …

Macrophages are a major component of the leukocyte infiltrate of tumors and play a pivotal
role in the progression of hepatocellular carcinoma (HCC). However, the molecular …

IL-8 (also known as neutrophil-activating peptide 1) is recognized as a potent effector of
neutrophil functions. Several different cell types that contact blood, namely T lymphocytes …

The production of tumour necrosis factor alpha (TNF alpha) and interleukin-6 by human
antral mucosa during short term culture in vitro has been measured by enzyme linked …

Cellular constituents of the alveolar-capillary wall may be key participants in the recruitment
of polymorphonuclear leukocytes to the lung through the generation of the novel neutrophil …

Chemotactic factors released at foci of injury and various types of inflammation are thought
to mediate directed migration of leukocytes into tissues. Since the identity of the infiltrating …