Gut microbiota-derived metabolites as key actors in inflammatory bowel disease
A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …
the pathogenesis of disease, has been identified over the past two decades. One of the …
Gut microbiota regulation of tryptophan metabolism in health and disease
The gut microbiota is a crucial actor in human physiology. Many of these effects are
mediated by metabolites that are either produced by the microbes or derived from the …
mediated by metabolites that are either produced by the microbes or derived from the …
Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity
Innate lymphoid cells (ILCs) and CD4+ T cells produce IL-22, which is critical for intestinal
immunity. The microbiota is central to IL-22 production in the intestines; however, the factors …
immunity. The microbiota is central to IL-22 production in the intestines; however, the factors …
Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut
MF Laursen, M Sakanaka, N von Burg, U Mörbe… - Nature …, 2021 - nature.com
Breastfeeding profoundly shapes the infant gut microbiota, which is critical for early life
immune development, and the gut microbiota can impact host physiology in various ways …
immune development, and the gut microbiota can impact host physiology in various ways …
Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease
V Rothhammer, FJ Quintana - Nature Reviews Immunology, 2019 - nature.com
The environment, diet, microbiota and body's metabolism shape complex biological
processes in health and disease. However, our understanding of the molecular pathways …
processes in health and disease. However, our understanding of the molecular pathways …
Impact of the gut microbiota on intestinal immunity mediated by tryptophan metabolism
The gut microbiota influences the health of the host, especially with regard to gut immune
homeostasis and the intestinal immune response. In addition to serving as a nutrient …
homeostasis and the intestinal immune response. In addition to serving as a nutrient …
Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions
B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …
The biology of innate lymphoid cells
D Artis, H Spits - Nature, 2015 - nature.com
The innate immune system is composed of a diverse array of evolutionarily ancient
haematopoietic cell types, including dendritic cells, monocytes, macrophages and …
haematopoietic cell types, including dendritic cells, monocytes, macrophages and …
Homeostatic immunity and the microbiota
Y Belkaid, OJ Harrison - Immunity, 2017 - cell.com
The microbiota plays a fundamental role in the induction, education, and function of the host
immune system. In return, the host immune system has evolved multiple means by which to …
immune system. In return, the host immune system has evolved multiple means by which to …