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Biochemistry and molecular biology of flaviviruses
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
[HTML][HTML] Current status of Zika virus vaccines: successes and challenges
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico
Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …
Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region
The clinical outcomes associated with Zika virus (ZIKV) in the Americas have been well
documented, but other aspects of the pandemic, such as attack rates and risk factors, are …
documented, but other aspects of the pandemic, such as attack rates and risk factors, are …
Intrinsic ADE: the dark side of antibody dependent enhancement during dengue infection
Dengue fever is an Aedes mosquito-borne illness caused by any one of the four different
dengue virus (DENV) serotypes (1–4) and manifests in the form of symptoms ranging from …
dengue virus (DENV) serotypes (1–4) and manifests in the form of symptoms ranging from …
A perspective on current flavivirus vaccine development: a brief review
SK Dutta, T Langenburg - Viruses, 2023 - mdpi.com
The flavivirus genus contains several clinically important pathogens that account for
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …
tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can …
Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge
J Wen, A Elong Ngono, JA Regla-Nava, K Kim… - Nature …, 2017 - nature.com
Zika virus (ZIKV) and dengue virus (DENV) are antigenically related flaviviruses that share
cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of …
cross-reactivity in antibody and T cell responses, and co-circulate in increasing numbers of …
Historical perspectives on flavivirus research
MR Holbrook - Viruses, 2017 - mdpi.com
The flaviviruses are small single-stranded RNA viruses that are typically transmitted by
mosquito or tick vectors. These “arboviruses” are found around the world and account for a …
mosquito or tick vectors. These “arboviruses” are found around the world and account for a …
Modulation of dengue/zika virus pathogenicity by antibody-dependent enhancement and strategies to protect against enhancement in zika virus infection
Antibody-dependent enhancement (ADE) is a phenomenon in which preexisting poorly
neutralizing antibodies leads to enhanced infection. It is a serious concern with mosquito …
neutralizing antibodies leads to enhanced infection. It is a serious concern with mosquito …
Extracellular vesicles from Zika virus‐infected cells display viral E protein that binds ZIKV‐neutralizing antibodies to prevent infection enhancement
F Zhao, Y Xu, N Liu, D Lv, Y Chen, Z Liu, X **… - The EMBO …, 2023 - embopress.org
Mosquito‐borne flaviviruses including Zika virus (ZIKV) represent a public health problem in
some parts of the world. Although ZIKV infection is predominantly asymptomatic or …
some parts of the world. Although ZIKV infection is predominantly asymptomatic or …