This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …

Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …

Microglia are key to maintaining the homeostasis of the brain. These immune cells of the
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …

Upon receipt in the dorsal horn (DH) of the spinal cord, nociceptive (pain-signalling)
information from the viscera, skin and other organs is subject to extensive processing by a …

The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

The endocannabinoids are a family of lipid messengers that engage the cell surface
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …

Truly global in scope and with contributions from leading researchers around the world, The
Handbook of Cannabis is the definitive resource on this fascinating drug. Combining …

The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …

CB2 was first considered to be the 'peripheral cannabinoid receptor'. This title was bestowed
based on its abundant expression in the immune system and presumed absence from the …