Bone marrow mesenchymal stromal cells (BMSCs), identified as pericytes comprising the
hematopoietic niche, are a group of heterogeneous cells composed of multipotent stem …

Skeletal elements have a diverse range of shapes and sizes specialized to their various
roles including protecting internal organs, locomotion, feeding, hearing, and vocalization …

A fundamental question in bone biology concerns the contributions of skeletal
stem/progenitor cells (SSCs) in the bone marrow versus the periosteum to bone repair. We …

Bone consists of separate inner endosteal and outer periosteal compartments, each with
distinct contributions to bone physiology and each maintaining separate pools of cells owing …

Critical-sized bone defects often lead to non-union and full-thickness defects of the
calvarium specifically still present reconstructive challenges. In this study, we show that …

Craniosynostosis is a group of disorders of premature calvarial suture fusion. The identity of
the calvarial stem cells (CSCs) that produce fusion-driving osteoblasts in craniosynostosis …

In elderly people particularly in postmenopausal women, inadequate bone formation by
osteoblasts originating from bone marrow mesenchymal stem cells (BMSCs) for …

Bone formation in mammals requires continuous production of osteoblasts throughout life. A
common molecular marker for all osteogenic mesenchymal progenitors has not been …

Craniosynostosis results from premature fusion of the cranial suture (s), which contain
mesenchymal stem cells (MSCs) that are crucial for calvarial expansion in coordination with …

Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to
the phylum Osteichthyes, from which their endoskeletal systems have been inherited …