Tailoring biomaterials for vaccine delivery

Y Zhuo, H Zeng, C Su, Q Lv, T Cheng, L Lei - Journal of …, 2024 - Springer
Biomaterials are substances that can be injected, implanted, or applied to the surface of
tissues in biomedical applications and have the ability to interact with biological systems to …

The quest for nanoparticle-powered vaccines in cancer immunotherapy

Z Sun, H Zhao, L Ma, Y Shi, M Ji, X Sun, D Ma… - Journal of …, 2024 - Springer
Despite recent advancements in cancer treatment, this disease still poses a serious threat to
public health. Vaccines play an important role in preventing illness by preparing the body's …

A Modular Self‐Assembling and Self‐Adjuvanting Multiepitope Peptide Nanoparticle Vaccine Platform to Improve the Efficacy and Immunogenicity of BCG

G Zhao, HD Sathkumara, S Miranda‐Hernandez… - Small, 2025 - Wiley Online Library
After more than a century since its initial development, Bacille Calmette‐Guérin (BCG)
remains the only licensed vaccine against tuberculosis (TB). Subunit boosters are …

Peptide vaccines as therapeutic and prophylactic agents for female-specific cancers: the current landscape

M Lekshmy, CR Dhanya, JSK Smrithi, JA Sindhurani… - Pharmaceuticals, 2023 - mdpi.com
Breast and gynecologic cancers are significant global threats to women's health and those
living with the disease require lifelong physical, financial, and social support from their …

Intramuscular Immunization with a Liposomal Multi-Epitope Chimeric Protein Induces Strong Cellular Immune Responses against Visceral Leishmaniasis

M Agallou, M Margaroni, E Karagouni - Vaccines, 2023 - mdpi.com
Control of the intracellular parasite Leishmania (L.) requires the activation of strong type 1
cellular immune responses. Towards this goal, in the present study, a multiepitope chimeric …

Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges

M Wang, F Yu, Y Zhang - Molecular Cancer, 2025 - Springer
Clinically, multimodal therapies are adopted worldwide for the management of cancer,
which continues to be a leading cause of death. In recent years, immunotherapy has firmly …

Nanotherapy for human papillomavirus-associated cancers: breakthroughs and challenges

J Lopes-Nunes, PA Oliveira, C Cruz - Trends in Pharmacological Sciences, 2024 - cell.com
Human papillomaviruses (HPVs) are well-known causative agents of several cancers, yet
selective therapies remain under investigation. Nanoparticles, for instance, are emerging as …

[HTML][HTML] Self-assembled monovalent lipidated mannose ligand as a standalone nanoadjuvant

UJ Nahar, J Wang, AO Shalash, L Lu, MT Islam… - Vaccine, 2024 - Elsevier
Subunit vaccines require an immunostimulant (adjuvant) and/or delivery system to induce
immunity. However, currently, available adjuvants are either too dangerous in terms of side …

Design and evaluation of a multi-epitope DNA vaccine against HPV16

L Zhu, X Cui, Z Yan, Y Tao, L Shi, X Zhang… - Human Vaccines & …, 2024 - Taylor & Francis
Cervical cancer, among the deadliest cancers affecting women globally, primarily arises
from persistent infection with high-risk human papillomavirus (HPV). To effectively combat …

Chemically Enhanced Peptide and Protein Therapeutics

C Díaz-Perlas, B Oller-Salvia - Pharmaceutics, 2023 - mdpi.com
Proteins and peptides are on the rise as therapeutic agents and represent a higher
percentage of approved drugs each year: 24% in 2021 vs. 13% in 2016 [1]. These classes of …