Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …

MRI features of cerebral small vessel disease (CSVD), ie white matter hyperintensities,
lacunes, microbleeds, perivascular spaces, and cerebral atrophy, may be associated with …

Alzheimer's disease (AD) is the most common form of dementia. AD brain pathology starts
decades before the onset of clinical symptoms. One early pathological hallmark is blood …

Importance Cerebral small vessel disease (SVD) causes a quarter of strokes and is the most
common pathology underlying vascular cognitive impairment and dementia. An important …

Aging plays a pivotal role in the pathogenesis of cerebral small vessel disease (CSVD),
contributing to the onset and progression of vascular cognitive impairment and dementia …

Cerebral microbleeds (CMBs) are defined as hypointense foci visible on T2*-weighted and
susceptible-weighted MRI sequences. CMBs are increasingly recognised with the …

Incident stroke has long been recognized to cause dementia shortly after the event. Patients
who survive stroke without early-onset poststroke dementia (PSD) are at a high risk of …

Background and Purpose Neurofilament light chain (NfL) is a blood marker for neuroaxonal
damage. We assessed the association between serum NfL and cerebral small vessel …

The human hippocampus is vulnerable to a range of degenerative conditions and as such,
accurate in vivo measurement of the hippocampus and hippocampal substructures via …