The genus Polygonum: An updated comprehensive review of its ethnomedicinal, phytochemical, pharmacological activities, toxicology, and phytopharmaceutical …

S Idoudi, A Tourrette, J Bouajila, M Romdhane… - Heliyon, 2024 - cell.com
Polygonum is a plant genus that includes annual and perennial species and is found at
various temperatures, from northern temperate regions to tropical and subtropical areas. The …

Pharmacological effects and therapeutic potential of natural compounds in neuropsychiatric disorders: An update

P Asgharian, C Quispe, J Herrera-Bravo… - Frontiers in …, 2022 - frontiersin.org
Neuropsychiatric diseases are a group of disorders that cause significant morbidity and
disability. The symptoms of psychiatric disorders include anxiety, depression, eating …

Biomarker triterpenoids of Centella asiatica as potential antidepressant agents: combining in vivo and in silico studies

Z Mando, H Mando, A Afzan, K Shaari, Z Hassan… - Behavioural Brain …, 2024 - Elsevier
Although there are various treatments available for depression, some patients may
experience resistance to treatment or encounter adverse effects. Centella asiatica (C …

Polygonum minus: A tropical medicinal herb with vast applications in food, agricultural, and medicinal fields

Z Yang, X Deng, Z Yang, M Han, N Ismail, KW Chan… - Food Bioscience, 2024 - Elsevier
Polygonum minus (PM) is a tropical medicinal herb that belongs to the family Polygonaceae,
widely distributed in Southeast Asia, such as Malaysia, Indonesia, and Thailand. This herb …

Antidepressant evaluation of Andrographis paniculata Nees extract and andrographolide in chronic unpredictable stress zebrafish model

Z Aldurrah, FSM Kauli, NA Rahim, Z Zainal… - … and Physiology Part C …, 2023 - Elsevier
Andrographis paniculata (A. paniculata) showed an anti-depressive effect in rodent models.
Zebrafish has recently emerged as a worthy complementary translational model for …

Exploring the anti-colon cancer potential of Polygonum minus: Integrating in vitro and in silico studies

Z Yang, Z Yang, MZA Bakar, X Deng - Food Bioscience, 2025 - Elsevier
Polygonum minus Huds (PM), commonly known as “laksa leaves”, is a valuable aromatic
plant used in food and traditional medicine, particularly in Southeast Asia. This study aimed …

Persicaria minor ameliorates the cognitive function of chronic cerebral hypoperfusion rats: Metabolomic analysis and potential mechanisms

LW Chun, RK Ramachandran, SFF Othman… - Behavioural Brain …, 2023 - Elsevier
Persicaria minor (P. minor) is a herbal plant with many uses in food, perfume, and the
medical industry. P. minor extract contains flavonoids with antioxidant and …

Anxiolytic-like effects of Pseudospondias microcarpa hydroethanolic leaf extract in zebrafish: Possible involvement of GABAergic and serotonergic pathways

DW Adongo, CK Benneh, A Tandoh, RP Biney… - Natural Products and …, 2023 - Springer
Pseudospondias microcarpa is used in ethnomedicine to manage central nervous system
diseases. The hydroethanolic extract (PME) from the leaves of the plant has shown …

Mechanistic insight into the antistress potential of eugenol: Modulation of the monoaminergic system in chronic unpredictable stress zebrafish model

P Choudhary, P Meena, KK Saini… - Chemical Biology …, 2025 - pubs.thesciencein.org
The unwanted side effects associated with existing therapeutics against anxiety disorder
warrants further preclinical investigations to discover new drug candidates. Herein, we …

Buspirone administration: Influence on growth, spawning, immune response, and stress in female goldfish (Carassius auratus)

H Abdollahpour, NJ Pastaki, M Karimzadeh, H Zamani - Heliyon, 2024 - cell.com
The current study evaluated the impact of buspirone supplementation on the growth,
physiology, stress response, spawning, and immunity in female goldfish (Carassius …