Colorectal cancer (CRC) is a multifactorial disease resulting from lifestyle, genetic, and
environmental factors. There are hereditary and non-hereditary CRC types; however, the …

Colorectal cancer (CRC) is the third cancer among the known causes of cancer that impact
people. Although CRC drug options are imperfect, primary detection of CRC can play a key …

Genetically modified animals are vital for gaining a proper understanding of disease
mechanisms. Mice have long been the mainstay of basic research into a wide variety of …

The rhizomes of ginger have been in use in many forms of traditional and alternative
medicines. Besides being employed as condiment and flavoring agent, it is used in the …

Serrated adenocarcinoma is a recently described subset of colorectal cancer (CRC), which
account for about 10% of all CRCs and follows an alternative pathway in which serrated …

Understanding the etiology of metastasis is very important in clinical perspective, since it is
estimated that metastasis accounts for 90% of cancer patient mortality. Metastasis results …

Mutations in the KRAS oncogene represent one of the most prevalent genetic alterations in
colorectal cancer (CRC), the third leading cause of cancer-related death in the US. In …

Since antiquity, ginger or Zingiber officinale, has been used by humans for medicinal
purposes and as spice condiments to enhance flavor in cooking. Ginger contains many …

Colorectal cancer (CRC) is the third most common cancer type and the second cause of
death worldwide. The advancement in understanding molecular pathways involved in CRC …

The mechanistic target of rapamycin (mTOR) integrates growth factor signals with cellular
nutrient and energy levels and coordinates cell growth, proliferation and survival. A …