In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Osteoarthritis (OA) is a common joint disease with a high disability rate. In addition, OA not
only causes great physiological and psychological harm to patients, but also puts great …

The inappropriate regenerated fibrous cartilage and subchondral bone of the injured
chondral defect ultimately cause degeneration of the regenerated cartilage, which …

Osteochondral regeneration is an orchestrated process of inflammatory immunity, host cell
response, and implant degradation in tissue engineering. Here, the effects of a platelet-rich …

Repairing articular osteochondral defects present considerable challenges in self‐repair
due to the complex tissue structure and low proliferation of chondrocytes. Conventional …

Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …

Despite significant advances in osteochondral tissue engineering, it remains challenging to
successfully reconstruct native-like complex tissues organized in three-dimension with …

Tissue engineering is an interdisciplinary field that integrates medical, biological, and
engineering expertise to restore or regenerate the functionality of healthy tissues and …

Osteochondral defects cannot be adequately self-repaired due to the presence of the
sophisticated hierarchical structure and the lack of blood supply in cartilage. Thus, one of the …

Tissue engineering (TE) involves the combination of cells with scaffolding materials and
appropriate growth factors in order to regenerate or replace damaged and degenerated …