Role of inflammatory mechanisms in major depressive disorder: from etiology to potential pharmacological targets
BR Kouba, L de Araujo Borba, P Borges de Souza… - Cells, 2024 - mdpi.com
The involvement of central and peripheral inflammation in the pathogenesis and prognosis
of major depressive disorder (MDD) has been demonstrated. The increase of pro …
of major depressive disorder (MDD) has been demonstrated. The increase of pro …
Neuroprotection by agmatine: Possible involvement of the gut microbiome?
P Saha, S Panda, A Holkar, R Vashishth… - Ageing Research …, 2023 - Elsevier
Agmatine, an endogenous polyamine derived from L-arginine, elicits tremendous
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …
Near-infrared photobiomodulation combined with coenzyme Q10 for depression in a mouse model of restraint stress: reduction in oxidative stress, neuroinflammation …
This study was aimed to evaluate the effects of near-infrared (NIR) photobiomodulation
(PBM) combined with coenzyme Q 10 (CoQ 10) on depressive-like behavior, cerebral …
(PBM) combined with coenzyme Q 10 (CoQ 10) on depressive-like behavior, cerebral …
Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice
CH Chiu, CC Chyau, CC Chen, LY Lee… - International journal of …, 2018 - mdpi.com
Antidepressant-like effects of ethanolic extract of Hericium erinaceus (HE) mycelium
enriched in erinacine A on depressive mice challenged by repeated restraint stress (RS) …
enriched in erinacine A on depressive mice challenged by repeated restraint stress (RS) …
Plasma metabolites predict severity of depression and suicidal ideation in psychiatric patients-a multicenter pilot analysis
Evaluating the severity of depression (SOD), especially suicidal ideation (SI), is crucial in the
treatment of not only patients with mood disorders but also psychiatric patients in general …
treatment of not only patients with mood disorders but also psychiatric patients in general …
Chronic unpredictable mild stress decreases BDNF and NGF levels and Na+, K+-ATPase activity in the hippocampus and prefrontal cortex of mice: Antidepressant …
CR Jesse, F Donato, R Giacomeli, L Del Fabbro… - Neuroscience, 2015 - Elsevier
Our working hypothesis is that brain neurotrophins and brain Na+, K+-ATPase may be
strongly associated with the occurrence of depression in animals subjected to chronic …
strongly associated with the occurrence of depression in animals subjected to chronic …
C60 Fullerene Prevents Restraint Stress‐Induced Oxidative Disorders in Rat Tissues: Possible Involvement of the Nrf2/ARE‐Antioxidant Pathway
The effects of C60FAS (50 and 500 μg/kg) supplementation, in a normal physiological state
and after restraint stress exposure, on prooxidant/antioxidant balance in rat tissues were …
and after restraint stress exposure, on prooxidant/antioxidant balance in rat tissues were …
Hesperidin alleviates chronic restraint stress and lipopolysaccharide-induced Hippocampus and Frontal cortex damage in mice: Role of TLR4/NF-κB, p38 MAPK/JNK …
Stress and lipopolysaccharide (LPS) animal models are used for screening antidepressants
and anxiolytic drugs. However, the lacunae for their combination (Restraint stress; RS and …
and anxiolytic drugs. However, the lacunae for their combination (Restraint stress; RS and …
Pathophysiology linking depression and type 2 diabetes: psychotherapy, physical exercise, and fecal microbiome transplantation as damage control
Diabetes increases the likelihood of develo** depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …
this bidirectional association has somewhat managed to delineate the interplay among …
Repeated daily restraint stress induces adaptive behavioural changes in both adult and juvenile mice
AM Sadler, SJ Bailey - Physiology & behavior, 2016 - Elsevier
Chronic stress is known to be a risk factor for the development of depression and anxiety,
disorders which often begin during adolescence. Restraint stress is a commonly used …
disorders which often begin during adolescence. Restraint stress is a commonly used …