X-ray free-electron lasers for the structure and dynamics of macromolecules
HN Chapman - Annual review of biochemistry, 2019 - annualreviews.org
X-ray free-electron lasers provide femtosecond-duration pulses of hard X-rays with a peak
brightness approximately one billion times greater than is available at synchrotron radiation …
brightness approximately one billion times greater than is available at synchrotron radiation …
Recent notable approaches to study self‐assembly of nanoparticles with X‐ray scattering and electron microscopy
Self‐assembly of nanoparticles (NPs) has evolved into a powerful tool for the synthesis of
superstructures with tailored properties. The quality, diversity, and complexity of synthesized …
superstructures with tailored properties. The quality, diversity, and complexity of synthesized …
Megahertz single-particle imaging at the European XFEL
E Sobolev, S Zolotarev, K Giewekemeyer… - Communications …, 2020 - nature.com
The emergence of high repetition-rate X-ray free-electron lasers (XFELs) powered by
superconducting accelerator technology enables the measurement of significantly more …
superconducting accelerator technology enables the measurement of significantly more …
Autocorrelation analysis for cryo-EM with sparsity constraints: improved sample complexity and projection-based algorithms
The number of noisy images required for molecular reconstruction in single-particle
cryoelectron microscopy (cryo-EM) is governed by the autocorrelations of the observed …
cryoelectron microscopy (cryo-EM) is governed by the autocorrelations of the observed …
[PDF][PDF] Single-particle imaging without symmetry constraints at an X-ray free-electron laser
The analysis of a single-particle imaging (SPI) experiment performed at the AMO beamline
at LCLS as part of the SPI initiative is presented here. A workflow for the three-dimensional …
at LCLS as part of the SPI initiative is presented here. A workflow for the three-dimensional …
Electrospray sample injection for single-particle imaging with x-ray lasers
The possibility of imaging single proteins constitutes an exciting challenge for x-ray lasers.
Despite encouraging results on large particles, imaging small particles has proven to be …
Despite encouraging results on large particles, imaging small particles has proven to be …
[HTML][HTML] Perspectives on single particle imaging with x rays at the advent of high repetition rate x-ray free electron laser sources
X-ray free electron lasers (XFELs) now routinely produce millijoule level pulses of x-ray
photons with tens of femtoseconds duration. Such x-ray intensities gave rise to the idea that …
photons with tens of femtoseconds duration. Such x-ray intensities gave rise to the idea that …
[PDF][PDF] Considerations for three-dimensional image reconstruction from experimental data in coherent diffractive imaging
Diffraction before destruction using X-ray free-electron lasers (XFELs) has the potential to
determine radiation-damage-free structures without the need for crystallization. This article …
determine radiation-damage-free structures without the need for crystallization. This article …
DNA-based construction at the nanoscale: emerging trends and applications
The field of structural DNA nanotechnology has evolved remarkably—from the creation of
artificial immobile junctions to the recent DNA–protein hybrid nanoscale shapes—in a span …
artificial immobile junctions to the recent DNA–protein hybrid nanoscale shapes—in a span …
Form factor determination of biological molecules with X-ray free electron laser small-angle scattering (XFEL-SAS)
Free-electron lasers (FEL) are revolutionizing X-ray-based structural biology methods. While
protein crystallography is already routinely performed at FELs, Small Angle X-ray Scattering …
protein crystallography is already routinely performed at FELs, Small Angle X-ray Scattering …