A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation

W Kang, J Ferruzzi, CP Spatarelu, YL Han, Y Sharma… - Iscience, 2021 - cell.com
It is well established that the early malignant tumor invades surrounding extracellular matrix
(ECM) in a manner that depends upon material properties of constituent cells, surrounding …

Cellular contact guidance emerges from gap avoidance

ABC Buskermolen, T Ristori, D Mostert… - Cell Reports Physical …, 2020 - cell.com
In the presence of anisotropic biochemical or topographical patterns, cells tend to align in
the direction of these cues—a widely reported phenomenon known as" contact guidance." …

In Vitro Regulation of Collective Cell Migration: Understanding the Role of Physical and Chemical Microenvironments

CX Li, ZX Zhao, DB Su, DC Yin, YJ Ye - Progress in Biophysics and …, 2024 - Elsevier
Collective cell migration is the primary mode of cellular movement during embryonic
morphogenesis, tissue repair and regeneration, and cancer invasion. Distinct from single …

Azobenzene-based sinusoidal surface topography drives focal adhesion confinement and guides collective migration of epithelial cells

C Fedele, E Mäntylä, B Belardi, T Hamkins-Indik… - Scientific reports, 2020 - nature.com
Surface topography is a key parameter in regulating the morphology and behavior of single
cells. At multicellular level, coordinated cell displacements drive many biological events …

Topographical curvature is sufficient to control epithelium elongation

P Rougerie, L Pieuchot, RS Dos Santos, J Marteau… - Scientific reports, 2020 - nature.com
How biophysical cues can control tissue morphogenesis is a central question in biology and
for the development of efficient tissue engineering strategies. Recent data suggest that …

Emergence of bidirectional cell laning from collective contact guidance

M Lacroix, B Smeets, C Blanch-Mercader, S Bell… - Nature Physics, 2024 - nature.com
Directed collective cell migration is central to morphogenesis, wound healing and cancer
progression. Although the molecular anisotropy of the microenvironment guides this …

Preparation of graphene oxide coatings on textured Ti6Al4V by laser micromachining and electrophoretic deposition for improved biocompatibility

Z Yu, M Duan, J Hu, H Yang - Optics & Laser Technology, 2022 - Elsevier
Introducing textures and coatings to titanium alloy implant is conducive to improving
biocompatibility. In this paper, a two-step scheme comprising laser texturing process …

Collective vortical motion and vorticity reversals of self-propelled particles on circularly patterned substrates

H Wen, Y Zhu, C Peng, PBS Kumar, M Laradji - Physical Review E, 2023 - APS
The collective behavior of self-propelled particles (SPPs) under the combined effects of a
circularly patterned substrate and circular confinement is investigated through coarse …

Hs27 fibroblast response to contact guidance cues

C Kim, M Robitaille, J Christodoulides, Y Ng… - Scientific Reports, 2023 - nature.com
Contact guidance is the phenomena of how cells respond to the topography of their external
environment. The morphological and dynamic cell responses are strongly influenced by …

Three-dimensional pore network characterization of reconstructed extracellular matrix

S Park, S Lim, P Siriviriyakul, JS Jeon - Physical Review E, 2020 - APS
The extracellular matrix (ECM) has a fiber network that provides physical scaffolds to cells
and plays important roles by regulating cellular functions. Some previous works …