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Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds
HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
Novel therapeutic strategies: targeting epithelial–mesenchymal transition in colorectal cancer
Epithelial–mesenchymal transition (EMT) is a process during which cells lose their epithelial
characteristics, for instance apical–basal cell polarity and cell–cell contact, and gain …
characteristics, for instance apical–basal cell polarity and cell–cell contact, and gain …
Non-redundant functions of EMT transcription factors
MP Stemmler, RL Eccles, S Brabletz, T Brabletz - Nature cell biology, 2019 - nature.com
Epithelial–mesenchymal transition (EMT) is a crucial embryonic programme that is executed
by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and …
by various EMT transcription factors (EMT-TFs) and is aberrantly activated in cancer and …
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
Carcinoma cells residing in an intermediate phenotypic state along the epithelial–
mesenchymal (E–M) spectrum are associated with malignant phenotypes, such as …
mesenchymal (E–M) spectrum are associated with malignant phenotypes, such as …
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
X Zheng, JL Carstens, J Kim, M Scheible, J Kaye… - Nature, 2015 - nature.com
Diagnosis of pancreatic ductal adenocarcinoma (PDAC) is associated with a dismal
prognosis despite current best therapies; therefore new treatment strategies are urgently …
prognosis despite current best therapies; therefore new treatment strategies are urgently …
Regulation of EMT in colorectal cancer: a culprit in metastasis
T Vu, PK Datta - Cancers, 2017 - mdpi.com
Epithelial to mesenchymal transition (EMT) is a process during which cells lose their
epithelial characteristics, for instance cell polarity and cell–cell contact, and gain …
epithelial characteristics, for instance cell polarity and cell–cell contact, and gain …
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
Tumour-initiating cells (TICs) are responsible for metastatic dissemination and clinical
relapse in a variety of cancers,. Analogies between TICs and normal tissue stem cells have …
relapse in a variety of cancers,. Analogies between TICs and normal tissue stem cells have …
EMT and MET: necessary or permissive for metastasis?
Epithelial‐to‐mesenchymal transition (EMT) and its reverse mesenchymal‐to‐epithelial
transition (MET) have been suggested to play crucial roles in metastatic dissemination of …
transition (MET) have been suggested to play crucial roles in metastatic dissemination of …
An epithelial–mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR …
Purpose: Epithelial–mesenchymal transition (EMT) has been associated with metastatic
spread and EGF receptor (EGFR) inhibitor resistance. We developed and validated a robust …
spread and EGF receptor (EGFR) inhibitor resistance. We developed and validated a robust …
Epithelial–mesenchymal transition and its transcription factors
P Debnath, RS Huirem, P Dutta… - Bioscience …, 2022 - portlandpress.com
Epithelial–mesenchymal transition or EMT is an extremely dynamic process involved in
conversion of epithelial cells into mesenchymal cells, stimulated by an ensemble of …
conversion of epithelial cells into mesenchymal cells, stimulated by an ensemble of …