Polyphenols and their impact on the prevention of neurodegenerative diseases and development

I Grabska-Kobyłecka, P Szpakowski, A Król… - Nutrients, 2023 - mdpi.com
It is well known that neurodegenerative diseases' development and progression are
accelerated due to oxidative stress and inflammation, which result in impairment of …

[HTML][HTML] Polyphenols and neurodegenerative diseases: potential effects and mechanisms of neuroprotection

RA Arias-Sánchez, L Torner, B Fenton Navarro - Molecules, 2023 - mdpi.com
The increase in people's longevity has, consequently, led to more brain involvement and
neurodegenerative diseases, which can become complicated and lead to chronic …

[HTML][HTML] Neuroprotective effects of quercetin in Alzheimer's disease

H Khan, H Ullah, M Aschner, WS Cheang, EK Akkol - Biomolecules, 2019 - mdpi.com
Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic
potential. It is widely distributed among plants and found commonly in daily diets …

[HTML][HTML] Anti-obesity effects of polyphenol intake: Current status and future possibilities

M Boccellino, S D'Angelo - International journal of molecular sciences, 2020 - mdpi.com
The prevalence of obesity has steadily increased worldwide over the past three decades.
The conventional approaches to prevent or treat this syndrome and its associated …

Polyphenols in the treatment of autoimmune diseases

H Khan, A Sureda, T Belwal, S Çetinkaya, İ Süntar… - Autoimmunity …, 2019 - Elsevier
In addition to protecting body from infections and diseases, the immune system produces
auto-antibodies that can cause complex autoimmune disorders, such as Type I diabetes …

[HTML][HTML] Flaxseed lignans as important dietary polyphenols for cancer prevention and treatment: Chemistry, pharmacokinetics, and molecular targets

SF De Silva, J Alcorn - Pharmaceuticals, 2019 - mdpi.com
Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …

Targeting apoptosis and autophagy following spinal cord injury: Therapeutic approaches to polyphenols and candidate phytochemicals

F Abbaszadeh, S Fakhri, H Khan - Pharmacological Research, 2020 - Elsevier
Spinal cord injury (SCI) is a neurological disorder associated with the loss of sensory and
motor function. Understanding the precise dysregulated signaling pathways, especially …

Neuroprotective potentials of Lead phytochemicals against Alzheimer's disease with focus on oxidative stress-mediated signaling pathways: Pharmacokinetic …

M Ayaz, OF Mosa, A Nawaz, AAE Hamdoon… - Phytomedicine, 2024 - Elsevier
Background Alzheimer's diseases (AD) and dementia are among the highly prevalent
neurological disorders characterized by deposition of beta amyloid (Aβ) plaques, dense …

In vitro gastrointestinal digestion impact on stability, bioaccessibility and antioxidant activity of polyphenols from wild and commercial blackberries (Rubus spp.)

OA Sánchez-Velázquez, M Mulero… - Food & Function, 2021 - pubs.rsc.org
Gastrointestinal digestion (GID) is a physiological process that transforms the stability,
bioaccessibility and antioxidant activity (AOX) of polyphenols from blackberries (Rubus …

Role of dietary polyphenols in non-communicable chronic disease prevention, and interactions in food systems: An overview

M Zekrumah, P Begua, A Razak, J Wahab, N Moffo… - Nutrition, 2023 - Elsevier
Polyphenols is a major group of non-nutrients, considering their diversity, occurrence, and
biological properties. Polyphenols play essential roles in the prevention of chronic diseases …