Psoriatic arthritis (PsA) is a complex inflammatory disease with heterogeneous clinical
features, which complicates psoriasis in 30% of patients. There are no diagnostic criteria or …

Biological therapies are an effective treatment for a range of immune-mediated inflammatory
diseases (IMIDs), including rheumatoid arthritis, psoriasis, and inflammatory bowel …

Background: Psoriasis is a common, chronic, inflammatory, debilitating, systemic disease
with a great impact on healthcare systems worldwide. As targeted therapies have …

Summary Background The interleukin-23 (IL-23)/T-helper 17 cell pathway is implicated in
psoriatic arthritis pathogenesis. Guselkumab, an IL-23 inhibitor that specifically binds the IL …

Background Many patients with psoriatic arthritis have an inadequate response to tumor
necrosis factor (TNF) inhibitors. Guselkumab, a specific inhibitor of interleukin-23 (IL-23) via …

Abstract Objective To update the European League Against Rheumatism (EULAR)
recommendations for the pharmacological treatment of psoriatic arthritis (PsA). Methods …

Whereas the cellular and molecular features of human inflammatory skin diseases are well
characterized, their tissue context and systemic impact remain poorly understood. We thus …

Background: This study aimed to compare the Hospital Anxiety and Depression Scale
(HADS) and the Zung Self-Rating Anxiety/Depression Scale (SAS/SDS) in evaluating …

Importance Psoriasis, psoriatic arthritis, and inflammatory bowel disease, ie, Crohn disease
and ulcerative colitis, are chronic systemic immune-mediated disorders affecting an …

Background Psoriatic arthritis (PsA) is a multifaceted condition with a broad spectrum of
manifestations and a range of associated comorbidities. A notable segment of patients with …