HIV-associated central nervous system (CNS) injury continues to be clinically significant in
the modern era of HIV infection and therapy. A substantial proportion of patients with …

HIV can infect the brain and impair central nervous system (CNS) function. Combination
antiretroviral therapy (cART) has not eradicated CNS complications. HIV-associated …

Surface reconstruction methods allow advanced analysis of structural and functional brain
data beyond what can be achieved using volumetric images alone. Automated generation of …

Altered cortical surface complexity and gyrification differences may be a potentially sensitive
marker for several neurodevelopmental disorders. We propose to use spherical harmonic …

We develop a novel formulation for the notion of shape differences, aimed at providing
detailed information about the location and nature of the differences or distortions between …

The use of imaging markers to predict clinical outcomes can have a great impact in public
health. The aim of this article is to develop a class of generalized scalar-on-image …

Computational anatomy methods are now widely used in clinical neuroimaging to map the
profile of disease effects on the brain and its clinical correlates. In Alzheimer's disease (AD) …

Introduction The purpose of this study was to characterize brain volumetric differences in HIV
seropositive and seronegative men and to determine effects of age, cardiovascular risk, and …

The apolipoprotein E (APOE) e4 genotype is a powerful risk factor for late-onset Alzheimer's
disease (AD). In the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort, we …

In many areas of medicine, visualization research can help with task simplification,
abstraction or complexity reduction. A common visualization approach is to facilitate …