Piezoelectric biomaterials inspired by nature for applications in biomedicine and nanotechnology

S Chen, X Tong, Y Huo, S Liu, Y Yin, ML Tan… - Advanced …, 2024 - Wiley Online Library
Bioelectricity provides electrostimulation to regulate cell/tissue behaviors and functions. In
the human body, bioelectricity can be generated in electromechanically responsive tissues …

Nanoparticles Mediated the Diagnosis and Therapy of Glioblastoma: Bypass or Cross the Blood–Brain Barrier

X Song, H Qian, Y Yu - Small, 2023 - Wiley Online Library
Glioblastoma is one of the most aggressive central nervous system malignancies with high
morbidity and mortality. Current clinical approaches, including surgical resection …

Bimetallic Organic Frameworks of High Piezovoltage for Sono‐Piezo Dynamic Therapy

Q Wang, Y Tian, M Yao, J Fu, L Wang… - Advanced …, 2023 - Wiley Online Library
Piezoelectric materials produce charges to directly act on cancer medium or promote the
generation of reactive oxygen species (ROS) for novel tumor therapy triggered by …

Engineering MMP-2 activated nanoparticles carrying B7-H3 bispecific antibodies for ferroptosis-enhanced glioblastoma immunotherapy

R Fan, C Chen, M Mu, D Chuan, H Liu, H Hou… - ACS …, 2023 - ACS Publications
Administration of bispecific antibodies (biAbs) in tumor therapy is limited by their short half-
life and off-target toxicity. Optimized strategies or targets are needed to overcome these …

Blood–Brain Barrier-Penetrative Fluorescent Anticancer Agents Triggering Paraptosis and Ferroptosis for Glioblastoma Therapy

J Wang, M Cao, L Han, P Shangguan… - Journal of the …, 2024 - ACS Publications
Currently used drugs for glioblastoma (GBM) treatments are ineffective, primarily due to the
significant challenges posed by strong drug resistance, poor blood–brain barrier (BBB) …

A Biodegradable Piezoelectric Sensor for Real‐Time Evaluation of the Motor Function Recovery After Nerve Injury

Y Shan, E Wang, X Cui, Y ** stem cells with wireless electrical nanopatches for traumatic brain injury therapy
L Wang, J Du, Q Liu, D Wang, W Wang, M Lei… - Nature …, 2024 - nature.com
Electrical stimulation holds promise for enhancing neuronal differentiation of neural stem
cells to treat traumatic brain injury. However, once the stem cells leave the stimulating …

Selective activation of cells by piezoelectric molybdenum disulfide nanosheets with focused ultrasound

CH Fan, HC Tsai, YS Tsai, HC Wang, YC Lin… - ACS …, 2023 - ACS Publications
An accurate method for neural stimulation within the brain could be very useful for treating
brain circuit dysfunctions and neurological disorders. With the aim of develo** such a …

Ultrasound‐Sensitive Intelligent Nanosystems: A Promising Strategy for the Treatment of Neurological Diseases

X Pan, W Huang, G Nie, C Wang… - Advanced Materials, 2024 - Wiley Online Library
Neurological diseases are a major global health challenge, affecting hundreds of millions of
people worldwide. Ultrasound therapy plays an irreplaceable role in the treatment of …

Janus microparticles-based targeted and spatially-controlled piezoelectric neural stimulation via low-intensity focused ultrasound

M Han, E Yildiz, U Bozuyuk, A Aydin, Y Yu… - Nature …, 2024 - nature.com
Electrical stimulation is a fundamental tool in studying neural circuits, treating neurological
diseases, and advancing regenerative medicine. Injectable, free-standing piezoelectric …