Behind the scenes of anthocyanins—From the health benefits to potential applications in food, pharmaceutical and cosmetic fields

JS Câmara, M Locatelli, JAM Pereira, H Oliveira… - Nutrients, 2022 - mdpi.com
Anthocyanins are widespread and biologically active water-soluble phenolic pigments
responsible for a wide range of vivid colours, from red (acidic conditions) to purplish blue …

[HTML][HTML] Dietary polyphenols and their relationship to the modulation of non-communicable chronic diseases and epigenetic mechanisms: A mini-review

FT Borsoi, IA Neri-Numa, WQ de Oliveira… - Food Chemistry …, 2023 - Elsevier
Abstract Chronic Non-Communicable Diseases (NCDs) have been considered a global
health problem, characterized as diseases of multiple factors, which are developed …

Therapeutic targeting of Ras/Raf/MAPK pathway by natural products: a systematic and mechanistic approach for neurodegeneration

MM Gravandi, S Abdian, M Tahvilian, A Iranpanah… - Phytomedicine, 2023 - Elsevier
Background Multiple dysregulated pathways are behind the pathogenesis of
neurodegenerative diseases (NDDs); however, the crucial targets are still unknown …

Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

[HTML][HTML] Chronic consumption of cranberries (Vaccinium macrocarpon) for 12 weeks improves episodic memory and regional brain perfusion in healthy older adults: a …

E Flanagan, D Cameron, R Sobhan, C Wong… - Frontiers in …, 2022 - frontiersin.org
Background: Ageing is highly associated with cognitive decline and modifiable risk factors
such as diet are believed to protect against this process. Specific dietary components and in …

Enhancing the cognitive effects of flavonoids with physical activity: is there a case for the gut microbiome?

CL Cheatham, DC Nieman, AP Neilson… - Frontiers in …, 2022 - frontiersin.org
Age-related cognitive changes can be the first indication of the progression to dementias,
such as Alzheimer's disease. These changes may be driven by a complex interaction of …

Molecular bases for the use of functional foods in the management of healthy aging: Berries, curcumin, virgin olive oil and honey; three realities and a promise

MD Navarro-Hortal, JM Romero-Márquez… - Critical Reviews in …, 2023 - Taylor & Francis
As the number of older people has grown in recent decades, the search for new approaches
to manage or delay aging is also growing. Among the modifiable factors, diet plays a crucial …

Effect of polyphenols on inflammation related to cognitive function: a systematic review and meta-analysis of human randomized controlled trials

C Mekhora, DJ Lamport… - Nutrition and Healthy …, 2024 - journals.sagepub.com
BACKGROUND: The decline of cognitive function could in part be caused by an increase in
inflammation. Polyphenols have been widely investigated due to their anti-inflammatory …

A Randomized, Double-Blind, Placebo-Controlled Study of an Anthocyanin-Rich Functional Ingredient on Cognitive Function and Eye Dryness in Late Adulthood …

J Wattanathorn, T Tong-Un, W Thukham-Mee… - Nutrients, 2023 - mdpi.com
Due to the rising demand for supplements targeting cognitive enhancement and dry eye
together with the health benefits of anthocyanins, we have developed a functional soup …

Neuroprotective effect of Eugenia uniflora against intranasal MPTP-induced memory impairments in rats: the involvement of pro-BDNF/p75NTR pathway

ASP Savall, EM Fidelis, JD de Mello, CB Quines… - Life sciences, 2023 - Elsevier
Parkinson's disease is a multisystemic neurodegenerative disorder that includes motor and
non-motor symptoms, and common symptoms include memory loss and learning difficulties …