Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
Intracellular delivery by membrane disruption: mechanisms, strategies, and concepts
Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
biomedical discoveries. It is also becoming increasingly important in industrial and medical …
A 2-DOF needle insertion device using inertial piezoelectric actuator
Insertion into delicate tissue, such as retina vein occlusion, cell manipulation, and
vitreoretinal injection, poses challenges to surgeons and biomedical researchers due to the …
vitreoretinal injection, poses challenges to surgeons and biomedical researchers due to the …
Zebrafish as a preclinical in vivo screening model for nanomedicines
The interactions of nanomedicines with biological environments is heavily influenced by
their physicochemical properties. Formulation design and optimization are therefore key …
their physicochemical properties. Formulation design and optimization are therefore key …
Zebrafish embryos and larvae: a new generation of disease models and drug screens
Technological innovation has helped the zebrafish embryo gain ground as a disease model
and an assay system for drug screening. Here, we review the use of zebrafish embryos and …
and an assay system for drug screening. Here, we review the use of zebrafish embryos and …
Multi-functional graphene as an in vitro and in vivo imaging probe
A strategy has been developed for the synthesis of multi-functional graphene (MFG) using
green synthetic approach and explored its biomedical application as a promising fluorescent …
green synthetic approach and explored its biomedical application as a promising fluorescent …
Nanonewton force-controlled manipulation of biological cells using a monolithic MEMS microgripper with two-axis force feedback
As mechanical end-effectors, microgrippers enable the pick–transport–place of micrometer-
sized objects, such as manipulation and positioning of biological cells in an aqueous …
sized objects, such as manipulation and positioning of biological cells in an aqueous …
Microinjection in biomedical applications: An effortless autonomous omnidirectional microinjection system
Thanks to the advancements in micro-and nanomechatronics techniques, the capability to
inject foreign materials into target locations inside biosamples has become increasingly …
inject foreign materials into target locations inside biosamples has become increasingly …
Robotic cell injection system with position and force control: Toward automatic batch biomanipulation
HB Huang, D Sun, JK Mills… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
Biological cell injection is laborious work that requires lengthy training and suffers from a low
success rate. In this paper, a robotic cell-injection system for automatic injection of batch …
success rate. In this paper, a robotic cell-injection system for automatic injection of batch …
Microinjection as a tool of mechanical delivery
Y Zhang, LC Yu - Current opinion in biotechnology, 2008 - Elsevier
Microinjection to single cells has been widely used in the studies of transduction-challenged
cells, transgenic animal production, and in vitro fertilization to mechanically transfer DNAs …
cells, transgenic animal production, and in vitro fertilization to mechanically transfer DNAs …