[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

B Killingley, AJ Mann, M Kalinova, A Boyers… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …

Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines

A Sette, S Crotty - Immunological reviews, 2022 - Wiley Online Library
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Association between mRNA vaccination and COVID-19 hospitalization and disease severity

MW Tenforde, WH Self, K Adams, M Gaglani, AA Ginde… - Jama, 2021 - jamanetwork.com
Importance A comprehensive understanding of the benefits of COVID-19 vaccination
requires consideration of disease attenuation, determined as whether people who develop …

Correlates of protection against SARS‐CoV‐2 infection and COVID‐19 disease

D Goldblatt, G Alter, S Crotty… - Immunological Reviews, 2022 - Wiley Online Library
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …

Clinical update on COVID-19 for the emergency clinician: Presentation and evaluation

B Long, BM Carius, S Chavez, SY Liang… - The American journal of …, 2022 - Elsevier
Introduction Coronavirus disease of 2019 (COVID-19) has resulted in millions of cases
worldwide. As the pandemic has progressed, the understanding of this disease has evolved …

[HTML][HTML] Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)

A Aleem, AS Ab, AK Slenker - 2021 - europepmc.org
Objectives: Describe the clinical manifestations, including extrapulmonary manifestations of
COVID-19. Outline the latest treatments available in the management of COVID-19 …

Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: a self-controlled case series and matched cohort study

I Katsoularis, O Fonseca-Rodríguez, P Farrington… - The Lancet, 2021 - thelancet.com
Background COVID-19 is a complex disease targeting many organs. Previous studies
highlight COVID-19 as a probable risk factor for acute cardiovascular complications. We …

Estimated transmissibility and impact of SARS-CoV-2 lineage B. 1.1. 7 in England

NG Davies, S Abbott, RC Barnard, CI Jarvis… - Science, 2021 - science.org
INTRODUCTION Several novel variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), the virus that causes COVID-19, emerged in late 2020. One of these, Variant …